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Results for

""NAV1.8 Voltage-Gated Sodium Channel""[mesh_terms]

27 Results

Searching titles within these results

Clinical Implications of Loss-of-Function Variants in 169 610 Exomes Representing the General Population.

Christian Paludan-Müller, Simon Larsen, Gustav Ahlberg, Laura Andreasen, Laia M Monfort, Jesper H Svendsen, Thomas Jespersen, Henning Bundgaard, Jørgen K Kanters, Morten S Olesen

Circulation. Genomic and precision medicine 2022;15(1):e003574

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Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding.

Holger Scheib, Iain McLay, Nicolas Guex, Jeff J Clare, Frank E Blaney, Tim J Dale, Simon N Tate, Graeme M Robertson

Journal of molecular modeling 2006;12(6):813-22

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Abstract

From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.

Malou van den Boogaard, Phil Barnett, Vincent M Christoffels

Trends in cardiovascular medicine 2014;24(3):99-104

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Abstract

'Mature' resting membrane potentials in human-induced pluripotent stem cell-derived cardiomyocytes: fact or artefact?

Arie O Verkerk, Carol Ann Remme

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2020;21(12):1928

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Chasing the Wrong Door for 30 Years: Is Suzetrigine the Key to Selective Pain Relief?

Robert Ancuceanu, Athena Ribigan, Adriana-Iuliana Anghel, Mihaela Dinu

Medicina (Kaunas, Lithuania) 2026;62(9):

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The Evolving Landscape of Small Fiber Neuropathy.

Grazia Devigili, Raffaella Lombardi, Daniele Cazzato, Giuseppe Lauria

Seminars in neurology 2025;45(1):132-144

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Advances in Experimental Medicine and Biology: Intrafascicular Local Anesthetic Injection Damages Peripheral Nerve-Induced Neuropathic Pain.

Kuang-Yi Tseng, Hung-Chen Wang, Lin-Li Chang, Kuang-I Cheng

Advances in experimental medicine and biology 2019;1099():65-76

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First-in-Human Phase I Trial of HRS-2129, a Selective Nav1.8 Inhibitor: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Healthy Subjects.

Jie Huang, Qian Wu, Saiying Wang, Jinlian Xie, Kunhong Deng, Shuang Yang, Xiaoyan Yang, Chuanpin Chen, Guoping Yang

Drug design, development and therapy 2026;20():628095

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In silico exploration of bioactive secondary metabolites with anesthetic effects on sodium channels Nav 1.7, 1.8, and 1.9 in painful human dental pulp.

Ravinder S Saini, Ravinder S Saini, Rayan Ibrahim H Binduhayyim, Rayan Ibrahim H Binduhayyim, Mohamed Saheer Kuruniyan, Mohamed Saheer Kuruniyan, Artak Heboyan, Artak Heboyan

Molecular pain 2025;21():17448069251327824

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Common and rare variants in SCN10A modulate the risk of atrial fibrillation.

Javad Jabbari, Morten S Olesen, Lei Yuan, Jonas B Nielsen, Bo Liang, Vincenzo Macri, Ingrid E Christophersen, Nikolaj Nielsen, Ahmad Sajadieh, Patrick T Ellinor, Morten Grunnet, Stig Haunsø, Anders G Holst, Jesper H Svendsen, Thomas Jespersen

Circulation. Cardiovascular genetics 2015;8(1):64-73

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Channelopathy-related SCN10A gene variants predict cerebellar dysfunction in multiple sclerosis.

Tina Roostaei, Shokufeh Sadaghiani, Min Tae M Park, Rahil Mashhadi, Aria Nazeri, Sina Noshad, Mohammad Javad Salehi, Maryam Naghibzadeh, Abdorreza Naser Moghadasi, Mahsa Owji, Rozita Doosti, Amir Pejman Hashemi Taheri, Ali Shakouri Rad, Amirreza Azimi, M Mallar Chakravarty, Aristotle N Voineskos, Arash Nazeri, Mohammad Ali Sahraian

Neurology 2016;86(5):410-7

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Fifteen Genetic Loci Associated With the Electrocardiographic P Wave.

Ingrid E Christophersen, Jared W Magnani, Xiaoyan Yin, John Barnard, Lu-Chen Weng, Dan E Arking, Maartje N Niemeijer, Steven A Lubitz, Christy L Avery, Qing Duan, Stephan B Felix, Joshua C Bis, Kathleen F Kerr, Aaron Isaacs, Martina Müller-Nurasyid, Christian Müller, Kari E North, Alex P Reiner, Lesley F Tinker, Jan A Kors, Alexander Teumer, Astrid Petersmann, Moritz F Sinner, Petra Buzkova, Jonathan D Smith, David R Van Wagoner, Uwe Völker, Melanie Waldenberger, Annette Peters, Thomas Meitinger, Marian C Limacher, Kirk C Wilhelmsen, Bruce M Psaty, Albert Hofman, Andre Uitterlinden, Bouwe P Krijthe, Zhu-Ming Zhang, Renate B Schnabel, Stefan Kääb, Cornelia van Duijn, Jerome I Rotter, Nona Sotoodehnia, Marcus Dörr, Yun Li, Mina K Chung, Elsayed Z Soliman, Alvaro Alonso, Eric A Whitsel, Bruno H Stricker, Emelia J Benjamin, Susan R Heckbert, Patrick T Ellinor

Circulation. Cardiovascular genetics 2018;10(4):e001667

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Phenotypes in Brugada syndrome with different genotypes triggered by fever or inflammation using gene-edited iPSCs.

Yingrui Li, Lena Rose, Timo Prädel, Mandy Kleinsorge, Xuehui Fan, Zenghui Meng, Chen Yan, Rui Liu, Xinhao Lei, Binyi Zhao, Guoqiang Yang, Zhenxing Liao, Hendrik Dinkel, Alexandra Viktoria Busley, Rujia Zhong, Feng Zhang, Qiang Xu, Lasse Maywald, Assem Aweimer, Mengying Huang, Alexander Moscu-Gregor, Nazha Hamdani, Luca Schneider, Yeweynwuha Zemedi, Saltanat Zhazykbayeva, Alyssa Hohn, Zhen Yang, Lin Qiao, Andreas Mügge, Lukas Cyganek, Xiaobo Zhou, Ibrahim Akin, Ibrahim El-Battrawy

Stem cell research & therapy 2025;16(1):670

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Painful and painless channelopathies.

David L H Bennett, C Geoffrey Woods

The Lancet. Neurology 2014;13(6):587-99

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Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation.

Alvaro Alonso, Lu-Chen Weng, Amelia Weber Hall, Seung Hoan Choi, Sean J Jurgens, Jeffrey Haessler, Nathan A Bihlmeyer, Niels Grarup, Honghuang Lin, Alexander Teumer, Ruifang Li-Gao, Jie Yao, Xiuqing Guo, Jennifer A Brody, Martina Müller-Nurasyid, Katharina Schramm, Niek Verweij, Marten E van den Berg, Jessica van Setten, Aaron Isaacs, Julia Ramírez, Helen R Warren, Sandosh Padmanabhan, Jan A Kors, Rudolf A de Boer, Peter van der Meer, Moritz F Sinner, Melanie Waldenberger, Bruce M Psaty, Kent D Taylor, Uwe Völker, Jørgen K Kanters, Man Li, Marco V Perez, Ilonca Vaartjes, Michiel L Bots, Paul L Huang, Susan R Heckbert, Henry J Lin, Jelena Kornej, Patricia B Munroe, Cornelia M van Duijn, Folkert W Asselbergs, Bruno H Stricker, Pim van der Harst, Stefan Kääb, Annette Peters, Nona Sotoodehnia, Jerome I Rotter, Dennis O Mook-Kanamori, Marcus Dörr, Stephan B Felix, Allan Linneberg, Torben Hansen, Dan E Arking, Charles Kooperberg, Emelia J Benjamin, Kathryn L Lunetta, Patrick T Ellinor, Steven A Lubitz

Circulation. Genomic and precision medicine 2021;13(5):387-395

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Results: 1 – 15 / 27

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Results for ""NAV1.8 Voltage-Gated Sodium Channel""[mesh_terms]

Clinical Implications of Loss-of-Function Variants in 169 610 Exomes Representing the General Population.

Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding.

From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.

'Mature' resting membrane potentials in human-induced pluripotent stem cell-derived cardiomyocytes: fact or artefact?

Chasing the Wrong Door for 30 Years: Is Suzetrigine the Key to Selective Pain Relief?

The Evolving Landscape of Small Fiber Neuropathy.

Advances in Experimental Medicine and Biology: Intrafascicular Local Anesthetic Injection Damages Peripheral Nerve-Induced Neuropathic Pain.

First-in-Human Phase I Trial of HRS-2129, a Selective Nav1.8 Inhibitor: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Healthy Subjects.

In silico exploration of bioactive secondary metabolites with anesthetic effects on sodium channels Nav 1.7, 1.8, and 1.9 in painful human dental pulp.

Common and rare variants in SCN10A modulate the risk of atrial fibrillation.

Channelopathy-related SCN10A gene variants predict cerebellar dysfunction in multiple sclerosis.

Fifteen Genetic Loci Associated With the Electrocardiographic P Wave.

Phenotypes in Brugada syndrome with different genotypes triggered by fever or inflammation using gene-edited iPSCs.

Painful and painless channelopathies.

Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation.

Results for

""NAV1.8 Voltage-Gated Sodium Channel""[mesh_terms]