Clinical Implications of Loss-of-Function Variants in 169 610 Exomes Representing the General Population.

Christian Paludan-Müller, Simon Larsen, Gustav Ahlberg, Laura Andreasen, Laia M Monfort, Jesper H Svendsen, Thomas Jespersen, Henning Bundgaard, Jørgen K Kanters, Morten S Olesen

Journal: Circulation. Genomic and precision medicine 2022;15(1):e003574

PMID: 35103494

Abstract

Address: Laboratory for Molecular Cardiology (C.P.-M., S.L., G.A., L.A., L.M.M., J.H.S., M.S.O.), Department of Cardiology, The Heart Centre, Copenhagen University Hospital - Rigshospitalet, Denmark.; Department of Biomedical Sciences (C.P.-M., S.L., G.A., L.A., L.M.M., T.J., M.S.O.), Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.; Department of Clinical Medicine (C.P.-M., G.A., L.M.M., J.H.S., H.B.), Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.; Laboratory for Molecular Cardiology (C.P.-M., S.L., G.A., L.A., L.M.M., J.H.S., M.S.O.), Department of Cardiology, The Heart Centre, Copenhagen University Hospital - Rigshospitalet, Denmark.; Department of Biomedical Sciences (C.P.-M., S.L., G.A., L.A., L.M.M., T.J., M.S.O.), Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.; Laboratory for Molecular Cardiology (C.P.-M., S.L., G.A., L.A., L.M.M., J.H.S., M.S.O.), Department of Cardiology, The Heart Centre, Copenhagen University Hospital - Rigshospitalet, Denmark.; Department of Clinical Medicine (C.P.-M., G.A., L.M.M., J.H.S., H.B.), Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.; Department of Biomedical Sciences (C.P.-M., S.L., G.A., L.A., L.M.M., T.J., M.S.O.), Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.; The Unit for Inherited Cardiac Diseases (H.B.), Department of Cardiology, The Heart Centre, Copenhagen University Hospital - Rigshospitalet, Denmark.; Department of Clinical Medicine (C.P.-M., G.A., L.M.M., J.H.S., H.B.), Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.; Laboratory of Experimental Cardiology, Department of Biomedical Sciences (J.K.K.), Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.