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Raymond Omollo, Neal Alexander, Tansy Edwards, Eltahir A G Khalil, Brima M Younis, Abuzaid A Abuzaid, Monique Wasunna, Njenga Njoroge, Dedan Kinoti, George Kirigi, Thomas P C Dorlo, Sally Ellis, Manica Balasegaram, Ahmed M Musa

Trials 2011;12():166

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Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti- Agents.

Lorenzo Tagliazucchi, Michele Tonelli, Giacomo Landi, Stefano Mangani, Joana Tavares, Cecilia Pozzi, Marco Rizzo, Anabela Cordeiro-da-Silva, Anna Carbone, Maria Paola Costi, Silvia Schenone, Valeria Francesconi, Claude U Konchie Simo, Giulia Saporito, Nuno Santarém

ACS infectious diseases 2024;10(8):2755-2774

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Structural Insights into the Development of Cycloguanil Derivatives as Pteridine-Reductase-1 Inhibitors.

Giacomo Landi, Pasquale Linciano, Chiara Borsari, Claudia P Bertolacini, Carolina B Moraes, Anabela Cordeiro-da-Silva, Sheraz Gul, Gesa Witt, Maria Kuzikov, Maria Paola Costi, Cecilia Pozzi, Stefano Mangani

ACS infectious diseases 2020;5(7):1105-1114

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Results for ""Trypanocidal Agents""[mesh_terms]

Metacaspases, autophagins and metallocarboxypeptidases: potential new targets for chemotherapy of the trypanosomiases.

Examination of multiple Trypanosoma cruzi targets in a new drug discovery approach for Chagas disease.

ELISA F29 -A therapeutic efficacy biomarker in Chagas disease: Evaluation in pediatric patients treated with nifurtimox and followed for 4 years post-treatment.

The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis.

A plethora of targets, a paucity of drugs: progress towards the development of novel chemotherapies for human African trypanosomiasis.

Predicting F NMR Chemical Shifts: A Combined Computational and Experimental Study of a Trypanosomal Oxidoreductase-Inhibitor Complex.

Withanolides from the genus Physalis: a review on their phytochemical and pharmacological aspects.

Trypanothione Reductase and Superoxide Dismutase as Current Drug Targets for Trypanosoma cruzi: An Overview of Compounds with Activity against Chagas Disease.

Indazoles: a new top seed structure in the search of efficient drugs against Trypanosoma cruzi.

Molecular dynamics simulations of peptide inhibitors complexed with Trypanosoma cruzi trypanothione reductase.

Evaluating Chagas disease progression and cure through blood-derived biomarkers: a systematic review.

Targeting trypanothione metabolism in trypanosomatid human parasites.

Safety and efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East Africa: study protocol for a randomized controlled trial.

Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti- Agents.

Structural Insights into the Development of Cycloguanil Derivatives as Pteridine-Reductase-1 Inhibitors.

Results for
""Trypanocidal Agents""[mesh_terms]