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Results for
""Thymidylate Synthase""[mesh_terms]

180 Results

Searching titles within these results

Flavin-dependent thymidylate synthase: N5 of flavin as a Methylene carrier.

Kalani Karunaratne, Nicholas Luedtke, Daniel M Quinn, Amnon Kohen

Archives of biochemistry and biophysics 2017;632():11-19

High-level QM/MM calculations support the concerted mechanism for Michael addition and covalent complex formation in thymidylate synthase.

Nopporn Kaiyawet, Richard Lonsdale, Thanyada Rungrotmongkol, Adrian J Mulholland, Supot Hannongbua

Journal of chemical theory and computation 2016;11(2):713-22

5,10-Methylene-5,6,7,8-tetrahydrofolate conformational transitions upon binding to thymidylate synthase: molecular mechanics and continuum solvent studies.

Adam Jarmuła, Piotr Cieplak, William R Montfort

Journal of computer-aided molecular design 2005;19(2):123-36

Dihydrofolate reductase, thymidylate synthase, and serine hydroxy methyltransferase: successful targets against some infectious diseases.

Agha Zeeshan Mirza, Rowaida Bakri, Hina Shamshad

Molecular biology reports 2022;49(7):6659-6691

The origin and diversification of eukaryotes: problems with molecular phylogenetics and molecular clock estimation.

Laura A Hug, Andrew J Roger

Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2006;361(1470):1039-54

Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya.

Jonathan Filée, Hubert F Becker, Lucille Mellottee, Rima Zein Eddine, Zhihui Li, Wenlu Yin, Jean-Christophe Lambry, Ursula Liebl, Hannu Myllykallio

Nature communications 2023;14(1):838

Regulation of thymidylate synthase: an approach to overcome 5-FU resistance in colorectal cancer.

Adarsh Kumar, Harshwardhan Singh, Ankit Kumar Singh, Suresh Thareja, Pradeep Kumar

Medical oncology (Northwood, London, England) 2022;40(1):3

Biochemical pharmacology of pemetrexed.

Alan Hilary Calvert

Oncology (Williston Park, N.Y.) 2005;18(13 Suppl 8):13-7

QM/MM calculations suggest a novel intermediate following the proton abstraction catalyzed by thymidylate synthase.

Zhen Wang, Silvia Ferrer, Vicent Moliner, Amnon Kohen

Biochemistry 2013;52(13):2348-58

Mechanisms and inhibition of uracil methylating enzymes.

Tatiana V Mishanina, Eric M Koehn, Amnon Kohen

Bioorganic chemistry 2012;43():37-43

A quantum mechanics/molecular mechanics study of the catalytic mechanism of the thymidylate synthase.

Natalia Kanaan, Sergio Martí, Vicent Moliner, Amnon Kohen

Biochemistry 2007;46(12):3704-13

Recent Design and Structure-Activity Relationship Studies on the Modifications of DHFR Inhibitors as Anticancer Agents.

Agnieszka Wróbel, Danuta Drozdowska

Current medicinal chemistry 2021;28(5):910-939

Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors.

A R Hanauske, V Chen, P Paoletti, C Niyikiza

The oncologist 2001;6(4):363-73

Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS).

Stefano Mangani, Giusy Tassone, Ludovica Lopresti, Cecilia Pozzi

Molecules (Basel, Switzerland) 2019;24(8):1638

Phase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients.

Maria Grazia Cusi, Cirino Botta, Pierpaolo Pastina, Maria Grazia Rossetti, Elena Dreassi, Giacomo Maria Guidelli, Antonella Fioravanti, Elodia Claudia Martino, Claudia Gandolfo, Marco Pagliuchi, Assunta Basile, Salvatore Francesco Carbone, Veronica Ricci, Lucia Micheli, Pierfrancesco Tassone, Pierosandro Tagliaferri, Luigi Pirtoli, Pierpaolo Correale

Cancer immunology, immunotherapy : CII 2015;64(9):1159-73

Results: 1 – 15 / 180

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