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Results for
""Oxo-Acid-Lyases""[mesh_terms]

18 Results

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More Than One HMG-CoA Lyase: The Classical Mitochondrial Enzyme Plus the Peroxisomal and the Cytosolic Ones.

Juan Pié, Beatriz Puisac, Gloria Bueno-Lozano, Paulino Gómez-Puertas, Rebeca Antoñanzas-Peréz, Cristina Lucia-Campos, Marta Gil-Salvador, María Arnedo, Ana Latorre-Pellicer

International journal of molecular sciences 2020;20(24):6124

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Phase 1, Single- and Multiple-Ascending-Dose, Food-Effect, and East Asian Subject Studies to Assess the Pharmacokinetics, Safety, and Tolerability of Bempedoic Acid, a Selective Inhibitor of Adenosine Triphosphate Citrate Lyase.

Benny M Amore, Diane E MacDougall, Jeffrey C Hanselman, Maurice G Emery

Clinical pharmacology in drug development 2023;12(10):1022-1035

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The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis.

Sanne G S Verberk, Jan Van den Bossche, Eicke Latz, Mario A Lauterbach, Kirsten L Kuiper

Trends in molecular medicine 2022;27(12):1095-1105

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Modelling the reaction course of N-acetylneuraminic acid synthesis from N-acetyl-D-glucosamine--new strategies for the optimisation of neuraminic acid synthesis.

Vera Zimmermann, Hans-Georg Hennemann, Thomas Daussmann, Udo Kragl

Applied microbiology and biotechnology 2007;76(3):597-605

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Manipulating respiratory levels in Escherichia coli for aerobic formation of reduced chemical products.

Jiangfeng Zhu, Ailen Sánchez, George N Bennett, Ka-Yiu San

Metabolic engineering 2012;13(6):704-12

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High-Level Production of Lysine in the Yeast Saccharomyces cerevisiae by Rational Design of Homocitrate Synthase.

Shota Isogai, Hiroshi Takagi, Romas Kazlauskas, Xiao Yi, Akira Nishimura, Yoichi Toyokawa, Jirasin Koonthongkaew, Hiroyuki Imanishi, Tomonori Matsushita

Applied and environmental microbiology 2021;87(15):e0060021

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Disorders of ketone production and utilization.

Michael A Kayer

Molecular genetics and metabolism 2006;87(4):281-3

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ATP-citrate lyase (ACLY) inhibitors as therapeutic agents: a patenting perspective.

Carlotta Granchi

Expert opinion on therapeutic patents 2022;32(7):731-742

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A metabolic node in action: chorismate-utilizing enzymes in microorganisms.

J Vanderleyden, F Dosselaere

Critical reviews in microbiology 2001;27(2):75-131

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An update on primary hyperoxaluria.

Bernd Hoppe

Nature reviews. Nephrology 2013;8(8):467-75

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Molecular genetics of HMG-CoA lyase deficiency.

Juan Pié, Eduardo López-Viñas, Beatriz Puisac, Sebastián Menao, Angeles Pié, Cesar Casale, Feliciano J Ramos, Fausto G Hegardt, Paulino Gómez-Puertas, Núria Casals

Molecular genetics and metabolism 2007;92(3):198-209

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Manifold decrease of sialic acid synthase in fetal Down syndrome brain.

T Gulesserian, E Engidawork, M Fountoulakis, G Lubec

Amino acids 2007;32(1):141-4

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Mutations in do Not Confer a Dominant Phenotype Manifesting as Kidney Stone Disease.

Mordechai Duvdevani, Yaacov Frishberg, Gary C Curhan, Shay Tzur, Ehud Gnessin, Ruth Bar-Gal, David B Mount, Martin R Pollak, Ruth Belostotsky, Efrat Ben-Shalom, Roi Bar

The Journal of urology 2021;205(5):1394-1399

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Homology modeling and molecular dynamics study on N-acetylneuraminate lyase.

Hui-Ying Chu, Qing-Chuan Zheng, Yong-Shan Zhao, Hong-Xing Zhang

Journal of molecular modeling 2009;15(3):323-8

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Recent advances in the identification and management of inherited hyperoxalurias.

David J Sas, Peter C Harris, Dawn S Milliner

Urolithiasis 2019;47(1):79-89

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Results: 1 – 15 / 18

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Results for ""Oxo-Acid-Lyases""[mesh_terms]

More Than One HMG-CoA Lyase: The Classical Mitochondrial Enzyme Plus the Peroxisomal and the Cytosolic Ones.

Phase 1, Single- and Multiple-Ascending-Dose, Food-Effect, and East Asian Subject Studies to Assess the Pharmacokinetics, Safety, and Tolerability of Bempedoic Acid, a Selective Inhibitor of Adenosine Triphosphate Citrate Lyase.

The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis.

Modelling the reaction course of N-acetylneuraminic acid synthesis from N-acetyl-D-glucosamine--new strategies for the optimisation of neuraminic acid synthesis.

Manipulating respiratory levels in Escherichia coli for aerobic formation of reduced chemical products.

High-Level Production of Lysine in the Yeast Saccharomyces cerevisiae by Rational Design of Homocitrate Synthase.

Disorders of ketone production and utilization.

ATP-citrate lyase (ACLY) inhibitors as therapeutic agents: a patenting perspective.

A metabolic node in action: chorismate-utilizing enzymes in microorganisms.

An update on primary hyperoxaluria.

Molecular genetics of HMG-CoA lyase deficiency.

Manifold decrease of sialic acid synthase in fetal Down syndrome brain.

Mutations in do Not Confer a Dominant Phenotype Manifesting as Kidney Stone Disease.

Homology modeling and molecular dynamics study on N-acetylneuraminate lyase.

Recent advances in the identification and management of inherited hyperoxalurias.

Results for
""Oxo-Acid-Lyases""[mesh_terms]