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Results for
""Organic Anion Transport Protein 1""[mesh_terms]

20 Results

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Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale.

Angelika Janaszkiewicz, Ágota Tóth, Quentin Faucher, Hélène Arnion, Nicolas Védrenne, Chantal Barin-Le Guellec, Pierre Marquet, Florent Di Meo

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023;160():114342

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Recent Advances in Synthetic Drugs and Natural Actives Interacting with OAT3.

Ying Chen, Hongyan Li, Ke Wang, Yousheng Wang

Molecules (Basel, Switzerland) 2023;28(12):4740

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Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug Interactions.

Marie-Emilie Willemin, Thomas K Van Der Made, Ils Pijpers, Lieve Dillen, Annett Kunze, Sophie Jonkers, Kathleen Steemans, An Tuytelaars, Frank Jacobs, Mario Monshouwer, Daniel Scotcher, Amin Rostami-Hodjegan, Aleksandra Galetin, Jan Snoeys

Clinical pharmacokinetics 2021;60(9):1187-1199

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Comparative analysis of the physiological and transport functions of various sources of renal proximal tubule cells under static and fluidic conditions in PhysioMimix T12 platform.

Courtney Sakolish, Ivan Rusyn, Allison N Dickey, Stephen S Ferguson, Haley L Moyer, Han-Hsuan D Tsai, Lucie C Ford, Piyush Bajaj, Remi Villenave, Philip Hewitt, Jason Stanko

Drug metabolism and disposition: the biological fate of chemicals 2025;53(1):100001

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Pyridoxic Acid as Endogenous Biomarker of Renal Organic Anion Transporter Activity: Population Variability and Mechanistic Modeling to Predict Drug-Drug Interactions.

Emi Kimoto, Manthena V S Varma, Sumathy Mathialagan, Aarzoo Thakur

CPT: pharmacometrics & systems pharmacology 2025;14(5):904-917

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Evidence for the Validity of Pyridoxic Acid (PDA) as a Plasma-Based Endogenous Probe for OAT1 and OAT3 Function in Healthy Subjects.

Hong Shen, Vinay K Holenarsipur, T Thanga Mariappan, Dieter M Drexler, Joseph L Cantone, Prabhakar Rajanna, Shashyendra Singh Gautam, Yueping Zhang, Jinping Gan, Petia A Shipkova, Punit Marathe, W Griffith Humphreys

The Journal of pharmacology and experimental therapeutics 2019;368(1):136-145

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Thyroid hormone transporters: recent advances.

Takaaki Abe, Takehiro Suzuki, Michiaki Unno, Taro Tokui, Sadayoshi Ito

Trends in endocrinology and metabolism: TEM 2002;13(5):215-20

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Differential interactions of the β-lactam cloxacillin with human renal organic anion transporters (OATs).

Sébastien Lalanne, Marc Le Vée, Florian Lemaitre, Pascal Le Corre, Marie-Clémence Verdier, Olivier Fardel

Fundamental & clinical pharmacology 2021;34(4):476-483

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Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans.

Kazuya Maeda, Ying Tian, Tomoe Fujita, Yasuhiko Ikeda, Yuji Kumagai, Tsunenori Kondo, Kazunari Tanabe, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara, Yuichi Sugiyama

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2015;59():94-103

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Evaluation of Adefovir PBPK Model to Assess Biomarker-Informed OAT1 Drug-Drug Interaction and Effect of Chronic Kidney Disease.

Daniel Scotcher, Amin Rostami-Hodjegan, Aleksandra Galetin, Shawn Pei Feng Tan, Huaying Wu

CPT: pharmacometrics & systems pharmacology 2025;14(5):964-974

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Investigation of Drug-Drug Interactions Between Ritobegron, a Selective β3 -Adrenoceptor Agonist, With Probenecid in Healthy Men.

Yoshikazu Abe, Yuki Nakano, Toru Kanazawa, Takao Furihata, Takuro Endo, Mamoru Kobayashi

Clinical pharmacology in drug development 2018;5(3):201-7

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Role of Organic Anion Transporters in the Uptake of Protein-Bound Uremic Toxins by Human Endothelial Cells and Monocyte Chemoattractant Protein-1 Expression.

Giane Favretto, Lauro M Souza, Paulo C Gregório, Regiane S Cunha, Rayana A P Maciel, Guilherme L Sassaki, Maria G Toledo, Roberto Pecoits-Filho, Wesley M Souza, Andréa E M Stinghen

Journal of vascular research 2017;54(3):170-179

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New Biomarkers for Renal Transporter-Mediated Drug-Drug Interactions: Metabolomic Effects of Cimetidine, Probenecid, Verapamil, and Rifampin in Humans.

Fabian Müller, Arne Gessner, Pia Wenisch, Peter Stopfer, Markus R Heinrich, Jörg König, Martin F Fromm

Clinical pharmacology and therapeutics 2024;117(1):130-142

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Drugs interacting with organic anion transporter-1 affect uptake of Tc-99m-mercaptoacetyl-triglycine (MAG3) in the human kidney: therapeutic drug interaction in Tc-99m-MAG3 diagnosis of renal function and possible application of Tc-99m-MAG3 for drug development.

Yasuhisa Fujibayashi, Tsuneo Saga, Chie Seki, Masayuki Inubushi, Yuichi Sugiyama, Noriko Takahara, Hiroyuki Kusuhara, Sumito Ito, Nobuyuki Oyama, Osamu Yokoyama

Nuclear medicine and biology 2014;40(5):643-50

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Roots against Cardiovascular Disease: Consideration of Herb-Drug Interactions.

Feng Chen, Li Li, Dan-Dan Tian

BioMed research international 2018;2017():9868694

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Results: 1 – 15 / 20

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Results for ""Organic Anion Transport Protein 1""[mesh_terms]

Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale.

Recent Advances in Synthetic Drugs and Natural Actives Interacting with OAT3.

Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug Interactions.

Comparative analysis of the physiological and transport functions of various sources of renal proximal tubule cells under static and fluidic conditions in PhysioMimix T12 platform.

Pyridoxic Acid as Endogenous Biomarker of Renal Organic Anion Transporter Activity: Population Variability and Mechanistic Modeling to Predict Drug-Drug Interactions.

Evidence for the Validity of Pyridoxic Acid (PDA) as a Plasma-Based Endogenous Probe for OAT1 and OAT3 Function in Healthy Subjects.

Thyroid hormone transporters: recent advances.

Differential interactions of the β-lactam cloxacillin with human renal organic anion transporters (OATs).

Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans.

Evaluation of Adefovir PBPK Model to Assess Biomarker-Informed OAT1 Drug-Drug Interaction and Effect of Chronic Kidney Disease.

Investigation of Drug-Drug Interactions Between Ritobegron, a Selective β3 -Adrenoceptor Agonist, With Probenecid in Healthy Men.

Role of Organic Anion Transporters in the Uptake of Protein-Bound Uremic Toxins by Human Endothelial Cells and Monocyte Chemoattractant Protein-1 Expression.

New Biomarkers for Renal Transporter-Mediated Drug-Drug Interactions: Metabolomic Effects of Cimetidine, Probenecid, Verapamil, and Rifampin in Humans.

Drugs interacting with organic anion transporter-1 affect uptake of Tc-99m-mercaptoacetyl-triglycine (MAG3) in the human kidney: therapeutic drug interaction in Tc-99m-MAG3 diagnosis of renal function and possible application of Tc-99m-MAG3 for drug development.

Roots against Cardiovascular Disease: Consideration of Herb-Drug Interactions.

Results for
""Organic Anion Transport Protein 1""[mesh_terms]