IMI2-PainCare-BioPain-RCT1: study protocol for a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by peripheral nerve excitability testing (NET).
Andrea Truini, Zahra Nochi, Hossein Pia, Petra Bloms-Funke, Irmgard Boesl, Ombretta Caspani, Sonya C Chapman, Francesca Fardo, Bernd Genser, Marcus Goetz, Anna V Kostenko, Caterina Leone, Thomas Li, André Mouraux, Bernhard Pelz, Esther Pogatzki-Zahn, Andreas Schilder, Erik Schnetter, Karin Schubart, Alexandre Stouffs, Irene Tracey, Iñaki F Troconiz, Johannes Van Niel, Jose Miguel Vela, Katy Vincent, Jan Vollert, Vishvarani Wanigasekera, Matthias Wittayer, Hatice Tankisi, Nanna B Finnerup, Keith G Phillips, Rolf-Detlef Treede
Trials 2022;23(1):163