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Results for
""Dealkylation""[mesh_terms]

11 Results

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Structural approach to the aging of phosphylated cholinesterases.

Oksana Lockridge, Florian Nachon, Patrick Masson

Chemico-biological interactions 2010;187(1-3):157-62

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Rate-limiting steps in cytochrome P450 catalysis.

F Peter Guengerich

Biological chemistry 2003;383(10):1553-64

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Regioselective enzymatic acylations of polyhydroxylated eudesmanes: semisynthesis, theoretical calculations, and biotransformation of cyclic sulfites.

A García-Granados, E Melguizo, A Parra, Y Simeó, B Viseras, J A Dobado, J Molina, J M Arias

The Journal of organic chemistry 2001;65(24):8214-23

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Dimethylsulfoniopropionate: its sources, role in the marine food web, and biological degradation to dimethylsulfide.

Duane C Yoch

Applied and environmental microbiology 2003;68(12):5804-15

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Ab initio QM/MM calculations show an intersystem crossing in the hydrogen abstraction step in dealkylation catalyzed by AlkB.

G Andrés Cisneros, Richard L Lord, Dong Fang

The journal of physical chemistry. B 2013;117(21):6410-20

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High-performance liquid chromatography-mass spectrometry analysis of diltiazem and 11 of its phase I metabolites in human plasma.

Leon Reubsaet, Grethe Helen Bøe, Espen Molden, Hege Christensen

Journal of pharmaceutical and biomedical analysis 2004;33(2):275-85

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A DFT study of nucleobase dealkylation by the DNA repair enzyme AlkB.

James W Gauld, Jorge Llano, Haining Liu

The journal of physical chemistry. B 2009;113(14):4887-98

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Simultaneous stereoselective analysis of tramadol and its primary phase I metabolites in plasma by liquid chromatography. Application to a pharmacokinetic study in humans.

Jose Ramón Azanza, Belén Sádaba, Emilio García-Quetglas, Miguel Angel Campanero

Journal of chromatography. A 2004;1031(1-2):219-28

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Excretion and metabolism of lersivirine (5-{[3,5-diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a next-generation non-nucleoside reverse transcriptase inhibitor, after administration of [14C]Lersivirine to healthy volunteers.

Manoli Vourvahis, Michelle Gleave, Angus N R Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins, Robert LaBadie

Drug metabolism and disposition: the biological fate of chemicals 2010;38(5):789-800

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Effect of Curcuma longa on CYP2D6- and CYP3A4-mediated metabolism of dextromethorphan in human liver microsomes and healthy human subjects.

Fahad Ibrahim Al-Jenoobi, Areej A Al-Thukair, Mohd Aftab Alam, Fawkeya A Abbas, Abdullah M Al-Mohizea, Khalid M Alkharfy, Saleh A Al-Suwayeh

European journal of drug metabolism and pharmacokinetics 2015;40(1):61-6

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The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein.

Irving W Wainer, David J Edwards, Marika Pasternyk Di Marco, Murray P Ducharme

Life sciences 2002;71(10):1149-60

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Results: 1 – 11 / 11

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Results for ""Dealkylation""[mesh_terms]

Structural approach to the aging of phosphylated cholinesterases.

Rate-limiting steps in cytochrome P450 catalysis.

Regioselective enzymatic acylations of polyhydroxylated eudesmanes: semisynthesis, theoretical calculations, and biotransformation of cyclic sulfites.

Dimethylsulfoniopropionate: its sources, role in the marine food web, and biological degradation to dimethylsulfide.

Ab initio QM/MM calculations show an intersystem crossing in the hydrogen abstraction step in dealkylation catalyzed by AlkB.

High-performance liquid chromatography-mass spectrometry analysis of diltiazem and 11 of its phase I metabolites in human plasma.

A DFT study of nucleobase dealkylation by the DNA repair enzyme AlkB.

Simultaneous stereoselective analysis of tramadol and its primary phase I metabolites in plasma by liquid chromatography. Application to a pharmacokinetic study in humans.

Excretion and metabolism of lersivirine (5-{[3,5-diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a next-generation non-nucleoside reverse transcriptase inhibitor, after administration of [14C]Lersivirine to healthy volunteers.

Effect of Curcuma longa on CYP2D6- and CYP3A4-mediated metabolism of dextromethorphan in human liver microsomes and healthy human subjects.

The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein.

Results for
""Dealkylation""[mesh_terms]