Results for
""Cytochrome P-450 CYP3A""[mesh_terms]

The Mechanism-Based Inactivation of CYP3A4 by Ritonavir: What Mechanism?

Nancy H C Loos, Jos H Beijnen, Alfred H Schinkel

International journal of molecular sciences 2022;23(17):9866

Versatile applicability of a grid-based CYP3A4 Template to understand the interacting mechanisms with the small-size ligands; part 3 of CYP3A4 Template study.

Yasushi Yamazoe, Takahiro Goto, Masahiro Tohkin

Drug metabolism and pharmacokinetics 2020;35(3):253-265

Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro.

David J Greenblatt, Karthik Venkatakrishnan, Jerold S Harmatz, Sarah J Parent, Lisa L von Moltke

Xenobiotica; the fate of foreign compounds in biological systems 2011;40(10):713-20

Cytochrome P450 3A4 inhibition by ketoconazole: tackling the problem of ligand cooperativity using molecular dynamics simulations and free-energy calculations.

Urban Bren, Chris Oostenbrink

Journal of chemical information and modeling 2012;52(6):1573-82

Effect of botanical immunomodulators on human CYP3A4 inhibition: implications for concurrent use as adjuvants in cancer therapy.

Dada Patil, Manish Gautam, Sunil Gairola, Suresh Jadhav, Bhushan Patwardhan

Integrative cancer therapies 2014;13(2):167-75

Evaluation of CYP3A-mediated drug-drug interactions with romidepsin in patients with advanced cancer.

Eric Laille, Manish Patel, Suzanne F Jones, Howard A Burris, Jeffrey Infante, Charlotte Lemech, Liangang Liu, Hendrik-Tobias Arkenau

Journal of clinical pharmacology 2016;55(12):1378-85

4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man.

D Lütjohann, M Marinova, B Schneider, J Oldenburg, K von Bergmann, T Bieber, I Björkhem, U Diczfalusy

International journal of clinical pharmacology and therapeutics 2010;47(12):709-15

Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism.

Haixing Li, Jed N Lampe

Archives of biochemistry and biophysics 2020;673():108078

The effects of ketoconazole and rifampin on the single-dose pharmacokinetics of crizotinib in healthy subjects.

Weiwei Tan, Akintunde Bello, Nicoletta Brega, Melissa O'Gorman, Huiping Xu

European journal of clinical pharmacology 2016;71(12):1441-9

Abiraterone inhibits 1α,25-dihydroxyvitamin D3 metabolism by CYP3A4 in human liver and intestine in vitro.

Emma S Tomlinson Guns, Hans Adomat, Mei Yieng Chin, Subrata Deb

The Journal of steroid biochemistry and molecular biology 2014;144 Pt A():50-8

Bergaptol, a Major Furocoumarin in Citrus: Pharmacological Properties and Toxicity.

Dunyaporn Trachootham, Pakkapong Phucharoenrak

Molecules (Basel, Switzerland) 2024;29(3):

Progress in the Consideration of Possible Sex Differences in Drug Interaction Studies.

Panjasaram Naidoo, Manoranjenni Chetty

Current drug metabolism 2019;20(2):114-123

Quinine compared to 4β-hydroxycholesterol and midazolam as markers for CYP3A induction by rifampicin.

Linda Björkhem-Bergman, Tobias Bäckström, Hanna Nylén, Yuko Rönquist-Nii, Eva Bredberg, Tommy B Andersson, Leif Bertilsson, Ulf Diczfalusy

Drug metabolism and pharmacokinetics 2015;29(4):352-5

Mechanism-based inhibition of human cytochrome P450-3A activity by grapefruit hybrids having low furanocoumarin content.

David J Greenblatt, Yanli Zhao, Michael J Hanley, Chunxian Chen, Jerold S Harmatz, Paul F Cancalon, Frederick G Gmitter

Xenobiotica; the fate of foreign compounds in biological systems 2013;42(12):1163-9