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Results for
""Coronavirus 3C Proteases""[mesh_terms]

78 Results

Searching titles within these results

Dissecting the effects of single amino acid substitutions in SARS-CoV-2 Mpro.

Liskin Swint-Kruse, Shwetha Sreenivasan, Joseph D Fontes

Protein science : a publication of the Protein Society 2025;34(8):e70225

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Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography.

Daniel W Kneller, Gwyndalyn Phillips, Kevin L Weiss, Swati Pant, Qiu Zhang, Hugh M O'Neill, Leighton Coates, Andrey Kovalevsky

The Journal of biological chemistry 2020;295(50):17365-17373

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Virtual Screening of Phytochemicals as Potential Inhibitors of SARS-CoV-2 Main Protease Enzyme.

Sajjad Ahmad, Khalid Miandad, Asad Ullah, Kashif Bashir, Saifullah Khan, Syed Ainul Abideen, Bilal Shaker, Metab Alharbi, Abdulrahman Alshammari, Mahwish Ali, Abdul Haleem

Molecules (Basel, Switzerland) 2022;27(22):8103

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Prediction of Binding Pose and Affinity of Nelfinavir, a SARS-CoV-2 Main Protease Repositioned Drug, by Combining Docking, Molecular Dynamics, and Fragment Molecular Orbital Calculations.

Shigenori Tanaka, Yusuke Kawashima, Kaori Fukuzawa, Yuji Mochizuki, Teruki Honma, Yuma Handa, Koji Okuwaki, Ryo Hatada, Yuto Komeiji, Takayuki Furuishi, Etsuo Yonemochi

The journal of physical chemistry. B 2024;128(10):2249-2265

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Computational molecular interaction between SARS-CoV-2 main protease and theaflavin digallate using free energy perturbation and molecular dynamics.

Manish Manish, Smriti Mishra, Ayush Anand, Naidu Subbarao

Computers in biology and medicine 2023;150():106125

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Generative artificial intelligence performs rudimentary structural biology modeling.

Christopher Markosian, Wadih Arap, Renata Pasqualini, Michael B Mathews, Stephen K Burley, Alexander M Ille

Scientific reports 2024;14(1):19372

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Pro108Ser mutation of SARS-CoV-2 3CL reduces the enzyme activity and ameliorates the clinical severity of COVID-19.

Toshiki Takenouchi, Yuko Kitagawa, Yasuaki Kabe, Hideyuki Saya, Kodai Abe, Susumu Uchiyama, Yuka W Iwasaki, Hirotsugu Ishizu, Yoshifumi Uwamino, Shunsuke Uno, Makoto Ishii, Takahiro Maruno, Masanori Noda, Mitsuru Murata, Naoki Hasegawa, Koichi Fukunaga, Masayuki Amagai, Haruhiko Siomi, Makoto Suematsu, Kenjiro Kosaki

Scientific reports 2022;12(1):1299

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Cys44 of SARS-CoV-2 3CL affects its catalytic activity.

Ilaria Iacobucci, Paola Storici, Carmine Talarico, Enzo Tramontano, Elisa Costanzi, Francesca Esposito, Flora Cozzolino, Maria Monti, Irene Cipollone, Daniela Iaconis, Gabriele Coppola, Stefano Morasso, Paolo Malune

International journal of biological macromolecules 2025;295():139590

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pH profiles of 3-chymotrypsin-like protease (3CLpro) from SARS-CoV-2 elucidate its catalytic mechanism and a histidine residue critical for activity.

Kenana Al Adem, Juliana C Ferreira, Samar Fadl, Wael M Rabeh

The Journal of biological chemistry 2023;299(2):102790

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In-silico drug repurposing for targeting SARS-CoV-2 main protease (M).

Shilpa Sharma, Shashank Deep

Journal of biomolecular structure & dynamics 2022;40(7):3003-3010

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Inhibition of SARS-CoV-2 main protease: a repurposing study that targets the dimer interface of the protein.

Hanife Pekel, Metehan Ilter, Ozge Sensoy

Journal of biomolecular structure & dynamics 2022;40(15):7167-7182

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Exploring covalent inhibitors of SARS-CoV-2 main protease: from peptidomimetics to novel scaffolds.

Mohammad A Ghattas, Noor Atatreh, Radwa E Mahgoub

Journal of enzyme inhibition and medicinal chemistry 2025;40(1):2460045

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A Review of the Current Landscape of SARS-CoV-2 Main Protease Inhibitors: Have We Hit the Bullseye Yet?

Guillem Macip, Pol Garcia-Segura, Júlia Mestres-Truyol, Bryan Saldivar-Espinoza, Gerard Pujadas, Santiago Garcia-Vallvé

International journal of molecular sciences 2022;23(1):259

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Novel Small-Molecule Scaffolds as Candidates against the SARS Coronavirus 2 Main Protease: A Fragment-Guided in Silico Approach.

Taufiq Rahman, Teresa L Augustin, Roxanna Hajbabaie, Matthew T Harper

Molecules (Basel, Switzerland) 2020;25(23):5501

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Rapid peptide-based screening on the substrate specificity of severe acute respiratory syndrome (SARS) coronavirus 3C-like protease by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Ling-Hon Matthew Chu, Wai-Yan Choy, Sau-Na Tsai, Zihe Rao, Sai-Ming Ngai

Protein science : a publication of the Protein Society 2006;15(4):699-709

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Results: 1 – 15 / 78

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Results for ""Coronavirus 3C Proteases""[mesh_terms]

Dissecting the effects of single amino acid substitutions in SARS-CoV-2 Mpro.

Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography.

Virtual Screening of Phytochemicals as Potential Inhibitors of SARS-CoV-2 Main Protease Enzyme.

Prediction of Binding Pose and Affinity of Nelfinavir, a SARS-CoV-2 Main Protease Repositioned Drug, by Combining Docking, Molecular Dynamics, and Fragment Molecular Orbital Calculations.

Computational molecular interaction between SARS-CoV-2 main protease and theaflavin digallate using free energy perturbation and molecular dynamics.

Generative artificial intelligence performs rudimentary structural biology modeling.

Pro108Ser mutation of SARS-CoV-2 3CL reduces the enzyme activity and ameliorates the clinical severity of COVID-19.

Cys44 of SARS-CoV-2 3CL affects its catalytic activity.

pH profiles of 3-chymotrypsin-like protease (3CLpro) from SARS-CoV-2 elucidate its catalytic mechanism and a histidine residue critical for activity.

In-silico drug repurposing for targeting SARS-CoV-2 main protease (M).

Inhibition of SARS-CoV-2 main protease: a repurposing study that targets the dimer interface of the protein.

Exploring covalent inhibitors of SARS-CoV-2 main protease: from peptidomimetics to novel scaffolds.

A Review of the Current Landscape of SARS-CoV-2 Main Protease Inhibitors: Have We Hit the Bullseye Yet?

Novel Small-Molecule Scaffolds as Candidates against the SARS Coronavirus 2 Main Protease: A Fragment-Guided in Silico Approach.

Rapid peptide-based screening on the substrate specificity of severe acute respiratory syndrome (SARS) coronavirus 3C-like protease by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Results for
""Coronavirus 3C Proteases""[mesh_terms]