Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).
Carl E Wagner, Peter W Jurutka, Pamela A Marshall, Thomas L Groy, Arjan van der Vaart, Joseph W Ziller, Julie K Furmick, Mark E Graeber, Erik Matro, Belinda V Miguel, Ivy T Tran, Jungeun Kwon, Jamie N Tedeschi, Shahram Moosavi, Amina Danishyar, Joshua S Philp, Reina O Khamees, Jevon N Jackson, Darci K Grupe, Syed L Badshah, Justin W Hart
Journal of medicinal chemistry 2009;52(19):5950-66