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Results for
""ATP Citrate (pro-S)-Lyase""[mesh_terms]

18 Results

Searching titles within these results

In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase.

Maurizio D Baroni, Sonia Colombo, Olivier Libens, Rani Pallavi, Marco Giorgio, Enzo Martegani

Apoptosis : an international journal on programmed cell death 2021;25(9-10):686-696

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The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis.

Sanne G S Verberk, Kirsten L Kuiper, Mario A Lauterbach, Eicke Latz, Jan Van den Bossche

Trends in molecular medicine 2022;27(12):1095-1105

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LDL-cholesterol reduction in patients with hypercholesterolemia by modulation of adenosine triphosphate-citrate lyase and adenosine monophosphate-activated protein kinase.

Roger S Newton, Sergey Filippov, Stephen L Pinkosky

Current opinion in lipidology 2015;25(4):309-15

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ATP-citrate lyase (ACLY) inhibitors as therapeutic agents: a patenting perspective.

Carlotta Granchi

Expert opinion on therapeutic patents 2022;32(7):731-742

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Discovery of potent ATP citrate lyase inhibitors from Tripterygium wilfordii Hook. f.: a structural and bioactivity analysis.

Feifei Huang, Dian Liu, Yang Han, Tao Hou, Jixia Wang, Yanfang Liu, Xinmiao Liang, Qing Xu, Yan Li, Boquan Qu, Xiaonian Li, Zhimou Guo, Fengbin Luo, Yunhui Zhu, Jiatao Feng

Phytochemistry 2025;239():114581

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Bempedoic acid, an inhibitor of ATP citrate lyase for the treatment of hypercholesterolemia: early indications and potential.

Julia Brandts, Kausik K Ray

Expert opinion on investigational drugs 2021;29(8):763-770

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Benzofurans and dibenzofurans from galls on twigs of the endangered Chinese endemic tree Parrotia subaequalis and their inhibitory properties against Staphylococcus aureus and ATP-citrate lyase.

Jin-Feng Hu, Yi Zang, Juan Xiong, Na Li, Jia Li, Peng-Jun Zhou, Xi-Ying Wu, Ze-Yu Zhao, Zhong-Shuai Sun, Yue-Ling Li, Yeun-Mun Choo, Ze-Xin Jin

Phytochemistry 2024;229():114309

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Efficacy and safety of a novel dual modulator of adenosine triphosphate-citrate lyase and adenosine monophosphate-activated protein kinase in patients with hypercholesterolemia: results of a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial.

Michael H Davidson, Harold E Bays, Diane E MacDougall, Christie M Ballantyne, Lorenzo A Dicarlo, Noah L Rosenberg, Janice Margulies, Roger S Newton

Journal of the American College of Cardiology 2013;62(13):1154-62

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Current drug targets for antihyperlipidemic therapy.

Kishor S Jain, Ranganath R Kulkarni, Dilpesh P Jain

Mini reviews in medicinal chemistry 2010;10(3):232-62

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A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects.

Chengyin Yu, Hongjie Qian, Jingya Li, Chen Yu, Liyu Liang, Jingying Jia, Yating Wang, Yanmei Liu, Yifan Zhang, Qian Chen, Yun Liu, Wei Li, Zhifu Xie, Sai Yan, Xiaoyin Lai, Yangming Zhang, Fajun Nan

Drug design, development and therapy 2025;19():1783-1794

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Lipids, Lipoproteins, and Cardiovascular Disease: Clinical Pharmacology Now and in the Future.

Alan Chait, Robert H Eckel

The Journal of clinical endocrinology and metabolism 2016;101(3):804-14

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Efficacy and Safety of Bempedoic Acid in Japanese Patients With Hypercholesterolemia　- A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study (the CLEAR-J Trial).

Yumiko Nakamura, Daisuke Yokota, Arihiro Kiyosue, Satoshi Yasuda, Shizuya Yamashita, Hitomi Fujita

Circulation journal : official journal of the Japanese Circulation Society 2025;89(8):1256-1265

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Phytochemical and biological studies on rare and endangered plants endemic to China. Part XV. Structurally diverse diterpenoids and sesquiterpenoids from the vulnerable conifer Pseudotsuga sinensis.

Ting Huang, Sheng-Hui Ying, Jing-Ya Li, Hao-Wei Chen, Yi Zang, Wen-Xuan Wang, Jia Li, Juan Xiong, Jin-Feng Hu

Phytochemistry 2020;169():112184

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Adenosine Triphosphate Citrate Lyase and Fatty Acid Synthesis Inhibition: A Narrative Review.

Robert P Giugliano, Freddy Duarte Lau

JAMA cardiology 2023;8(9):879-887

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Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.

Steven Zhao, Cholsoon Jang, Joyce Liu, Kahealani Uehara, Michael Gilbert, Luke Izzo, Xianfeng Zeng, Sophie Trefely, Sully Fernandez, Alessandro Carrer, Katelyn D Miller, Zachary T Schug, Nathaniel W Snyder, Terence P Gade, Paul M Titchenell, Joshua D Rabinowitz, Kathryn E Wellen

Nature 2020;579(7800):586-591

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Results: 1 – 15 / 18

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Results for ""ATP Citrate (pro-S)-Lyase""[mesh_terms]

In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase.

The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis.

LDL-cholesterol reduction in patients with hypercholesterolemia by modulation of adenosine triphosphate-citrate lyase and adenosine monophosphate-activated protein kinase.

ATP-citrate lyase (ACLY) inhibitors as therapeutic agents: a patenting perspective.

Discovery of potent ATP citrate lyase inhibitors from Tripterygium wilfordii Hook. f.: a structural and bioactivity analysis.

Bempedoic acid, an inhibitor of ATP citrate lyase for the treatment of hypercholesterolemia: early indications and potential.

Benzofurans and dibenzofurans from galls on twigs of the endangered Chinese endemic tree Parrotia subaequalis and their inhibitory properties against Staphylococcus aureus and ATP-citrate lyase.

Efficacy and safety of a novel dual modulator of adenosine triphosphate-citrate lyase and adenosine monophosphate-activated protein kinase in patients with hypercholesterolemia: results of a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial.

Current drug targets for antihyperlipidemic therapy.

A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects.

Lipids, Lipoproteins, and Cardiovascular Disease: Clinical Pharmacology Now and in the Future.

Efficacy and Safety of Bempedoic Acid in Japanese Patients With Hypercholesterolemia - A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study (the CLEAR-J Trial).

Phytochemical and biological studies on rare and endangered plants endemic to China. Part XV. Structurally diverse diterpenoids and sesquiterpenoids from the vulnerable conifer Pseudotsuga sinensis.

Adenosine Triphosphate Citrate Lyase and Fatty Acid Synthesis Inhibition: A Narrative Review.

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.

Results for
""ATP Citrate (pro-S)-Lyase""[mesh_terms]

Efficacy and Safety of Bempedoic Acid in Japanese Patients With Hypercholesterolemia　- A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study (the CLEAR-J Trial).