Heart failure with mitral valve regurgitation due to primary hyperoxaluria type 1: case report with review of the literature.

Luc Van Driessche, Annemieke Dhondt, Johan De Sutter

Journal: Acta cardiologica 2007;62(2):202-6

PMID: 17536611

Abstract

Primary hyperoxaluria type I (PH I) is a rare recessive autosomal disorder characterized by systemic calcium oxalate depositions, that results in renal failure and systemic oxalosis. We report a 38-year-old male with cardiac oxalosis, a severe complication of PHI, presenting with an infiltrative cardiomyopathy, secondary heart failure and severe mitral regurgitation, necessitating surgical repair to allow combined liver-kidney transplantation. We discuss pathogenesis, diagnostics and therapy of this clinical entity by reviewing literature.

Address: Department of Cardiology, University Hospital Ghent, Ghent, Belgium. [email protected]

DOI: 10.2143/AC.62.2.2020243

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https://medlineplus.gov/heartfailure.html

MeSH Terms: Adult, Cardiomyopathies, Echocardiography, Heart Failure, Heart Valve Prosthesis Implantation, Humans, Hyperoxaluria, Primary, Kidney Failure, Chronic, Male, Mitral Valve Insufficiency, Renal Dialysis, Tricuspid Valve Insufficiency