DRS is far less divergent than streptococcal inhibitor of complement of group A streptococcus.

Vivek Sagar, Rajesh Kumar, Nirmal K Ganguly, Thangam Menon, Anuradha Chakraborti

Journal: Journal of bacteriology 2007;189(7):2933-5

PMID: 17237170

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Abstract

When 100 group A streptococcus isolates were screened, drs, a variant of sic, was identified in emm12 and emm55 isolates. Molecular characterization showed that the drs gene sequence is highly conserved, unlike the sic gene sequence. However, the variation in gene size observed was due to the presence of extra internal repeat sequences.

Address: Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh, 160012 India.

DOI: 10.1128/JB.01619-06

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MeSH Terms: Amino Acid Sequence, Bacterial Proteins, Genetic Complementation Test, Genetic Variation, Molecular Sequence Data, Polymerase Chain Reaction, Streptococcus pyogenes