Integration of gel-based proteome data with pProRep.

Kris Laukens, Rune Matthiesen, Filip Lemière, Eddy Esmans, Harry Van Onckelen, Ole Nørregaard Jensen, Erwin Witters

Journal: Bioinformatics (Oxford, England) 2007;22(22):2838-40

PMID: 17032679

Full Text on Ovid Technologies, Inc. View on PubMed

Abstract

UNLABELLED

pProRep is a web application integrating electrophoretic and mass spectral data from proteome analyses into a relational database. The graphical web-interface allows users to upload, analyse and share experimental proteome data. It offers researchers the possibility to query all previously analysed datasets and can visualize selected features, such as the presence of a certain set of ions in a peptide mass spectrum, on the level of the two-dimensional gel.

AVAILABILITY

The pProRep package and instructions for its use can be downloaded from http://www.ptools.ua.ac.be/pProRep. The application requires a web server that runs PHP 5 (http://www.php.net) and MySQL. Some (non-essential) extensions need additional freely available libraries: details are described in the installation instructions.

Address: Laboratory of Plant Physiology and Plant Biochemistry, University of Antwerp Groenenborgerlaan 171, B-2020 Antwerp, Belgium. [email protected]

DOI: 10.1093/bioinformatics/btl487

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MeSH Terms: Computational Biology, Database Management Systems, Databases, Genetic, Databases, Protein, Electrophoresis, Gel, Two-Dimensional, Information Storage and Retrieval, Internet, Ions, Mass Spectrometry, Peptides, Programming Languages, Proteome, Proteomics, Software, User-Computer Interface