Clinical inquiries. What is the best treatment for mild to moderate acne?

Shobha Rao, Mehreen A Malik, Laura Wilder, Timothy Mott

Journal: The Journal of family practice 2006;55(11):994-6

PMID: 17090362

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Abstract

For mild comedonal acne, monotherapy with topical retinoids is the treatment of choice (strength of recommendation [SOR]: A). For moderate comedonal and mild to moderate papulopustular acne, combination therapy with either benzoyl peroxide or topical retinoids (adapalene [Differin], tazarotene [Tazorac], tretinoin [Retin-A]) plus topical antibiotics (erythromycin or clindamycin) is proven most effective (SOR: A). Six to 8 weeks should be allowed for most treatments to work before altering the regimen (SOR: A).

Address: University of Texas Southwestern Family Practice Residency, Dallas, TX, USA.

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MeSH Terms: Acne Vulgaris, Anti-Bacterial Agents, Benzoyl Peroxide, Clindamycin, Dermatologic Agents, Drug Therapy, Combination, Erythromycin, Humans, Retinoids