Endothelial dysfunction in cold type complex regional pain syndrome.

J Schattschneider, K Hartung, M Stengel, J Ludwig, A Binder, G Wasner, R Baron

Journal: Neurology 2006;67(4):673-5

PMID: 16924021

Abstract

The authors examined endothelial function in cold type chronic complex regional pain syndrome (CRPS) I using acetylcholine- and sodium nitroprusside-induced vasodilation combined with laser Doppler flowmetry in 14 patients and 10 controls. On the affected side, acetylcholine-induced vasodilation was significantly reduced in comparison to controls and the unaffected extremity. No significant differences were found after application of sodium nitroprusside. The results demonstrate impaired endothelial function in chronic CRPS I.

Address: Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Campus Kiel, Kiel, Germany. [email protected]

DOI: 10.1212/01.wnl.0000229931.40631.31

Link outs

Free resources

Medical:

https://medlineplus.gov/vasculardiseases.html

Subscription / membership required

Full Text Sources:

MeSH Terms: Acetylcholine, Adult, Aged, Cold Temperature, Endothelium, Vascular, Female, Humans, Hyperalgesia, Laser-Doppler Flowmetry, Male, Middle Aged, Nitroprusside, Reflex Sympathetic Dystrophy, Ultrasonography, Vascular Diseases, Vasodilator Agents