The aetiology of depression.

David Goldberg

Journal: Psychological medicine 2007;36(10):1341-7

PMID: 16740176

Full Text on Ovid Technologies, Inc. View on PubMed

Abstract

This review will start by considering studies of the genetic contribution to the liability to depression, and go on to consider some of the ways in which environmental factors can modify gene expression. This will lead on to the pathways by which the genetic factors also appear to control stressful life events in adolescence and adult life, and then to a consideration of causes that are entirely environmental. We will conclude by considering the causes of the gender differences in the prevalence of depression during adult life.

Address: Institute of Psychiatry, King's College, London, UK. [email protected]

DOI: 10.1017/S0033291706007665

Link outs

Free resources

Medical:

https://medlineplus.gov/depression.html

Subscription / membership required

Full Text Sources:

MeSH Terms: Child, Child Development, Chromosomes, Human, Pair 17, Depression, Environment, Female, Humans, Hypothalamo-Hypophyseal System, Life Change Events, Male, Personality, Pituitary-Adrenal System, Serotonin, Sex Factors, Twins