Genetics of type 2 diabetes.

Mark I McCarthy, Eleftheria Zeggini

Journal: Current diabetes reports 2006;6(2):147-54

PMID: 16542626

Abstract

After several years of uncertain progress, the stage is now set for a transformation in understanding the genetic landscape of type 2 diabetes. Advances in genome informatics, genotyping technology, and statistical methodology, allied to availability of large-scale clinical material, are having a salutary effect on susceptibility gene discovery. The advent of genuinely genome-wide association scans and the prospects for combining genetics with high-throughput genomics are additional sources of optimism for the future.

Address: Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital Campus, Old Road, Oxford OX3 7LJ, UK. [email protected]

DOI: 10.1007/s11892-006-0026-7

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https://dx.doi.org/10.1007/s11892-006-0026-7

MeSH Terms: Diabetes Mellitus, Type 2, Genetic Linkage, Genetic Research, Humans, PPAR gamma, Potassium Channels, Inwardly Rectifying, Proteins, Research Design