Effect of Tamarindus indica fruits on blood pressure and lipid-profile in human model: an in vivo approach.

A S M Maruf Iftekhar, Israt Rayhan, Mohiuddin Abdul Quadir, Sharif Akhteruzzaman, Abul Hasnat

Journal: Pakistan journal of pharmaceutical sciences 2007;19(2):125-9

PMID: 16751124

Abstract

Fruits of Tamarindus indica were evaluated for their effects on lipid profile, systolic and diastolic blood pressure and body weight in human subjects. Dried and pulverized pulp of T. indica fruits, at a dose of 15 mg/kg body weight, was found to reduce total cholesterol level (p = 0.031) and LDL-cholesterol level (p = 0.004) to a significant extent. Though the fruits exerted no conspicuous effect on body weight and systolic blood pressure, it significantly reduced the diastolic pressure as confirmed by independent sample t-test at 5% significance level.

Address: Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh.

MeSH Terms: Administration, Oral, Adult, Blood Pressure, Cholesterol, Cholesterol, LDL, Female, Fruit, Humans, Lipid Metabolism, Male, Middle Aged, Plant Extracts, Tamarindus, Triglycerides