Mononuclear copper active-oxygen complexes.

There have been significant advances in the understanding of the dioxygen-activation chemistry of mononuclear copper monooxygenases such as peptidylglycine alpha-amidating monooxygenase and dopamine beta-monooxygenase (DbetaM). Recent structural and spectroscopic studies on a series of biomimetic model compounds have provided new and valuable insights into the key reactive intermediates involved in the dioxygen processing at the mononuclear copper reaction centers in biological systems.