Effect of topical 1.25% povidone-iodine eyedrops used for prophylaxis of ophthalmia neonatorum on renal iodine excretion and thyroid-stimulating hormone level.

Ralph Richter, Harald Below, Ingrid Kadow, Axel Kramer, Cornelia Müller, Christoph Fusch

Journal: The Journal of pediatrics 2006;148(3):401-3

PMID: 16615978

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Abstract

The 1% silver nitrate, which has been used for preventing gonococcal conjunctivitis in the neonate, is not effective against Chlamydia trachomatis and may provoke eye irritation. It is not known whether the alternative topical agent, 1.25% povidone-iodine, can influence thyroid function. In this study, no influence of povidone-iodine on thyroid function was observed.

Address: Department of Neonatology and Pediatric Intensive Care, University of Greifswald, Germany.

DOI: 10.1016/j.jpeds.2005.10.024

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MeSH Terms: Administration, Topical, Anti-Infective Agents, Local, Female, Humans, Infant, Newborn, Iodides, Male, Ophthalmia Neonatorum, Ophthalmic Solutions, Povidone-Iodine, Prospective Studies, Silver Nitrate, Thyrotropin