Microglia in Central Control of Metabolism.

Jung Dae Kim, Francesca Copperi, Sabrina Diano

Journal: Physiology (Bethesda, Md.) 2023;39(1):0

PMID: 37962895

Abstract

Beyond their role as brain immune cells, microglia act as metabolic sensors in response to changes in nutrient availability, thus playing a role in energy homeostasis. This review highlights the evidence and challenges of studying the role of microglia in metabolism regulation.

Address: Institute of Human Nutrition, Columbia University Irving Medical Center, New York, New York, United States.; Department of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, New York, United States.; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, New York, United States.

DOI: 10.1152/physiol.00021.2023

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https://medlineplus.gov/obesity.html

MeSH Terms: Humans, Microglia, Obesity, Hypothalamus, Energy Metabolism, Homeostasis