Asymmetric oxidation by Gluconobacter oxydans.

Gao Keliang, Wei Dongzhi

Journal: Applied microbiology and biotechnology 2006;70(2):135-9

PMID: 16432743

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Abstract

Asymmetric oxidation is of great value and a major interest in both research and application. This review focuses on asymmetric oxidation of organic compounds by Gluconobacter oxydans. The microbe can be used for bioproduction of several kinds of important chiral compounds, such as vitamin C, 6-(2-hydroxyethyl)amino-6-deoxy-alpha-L-sorbofuranose, (S)-2-methylbutanoic acid, (R)-2-hydroxy-propionic acid and 5-keto-D-gluconic acid. Characteristics of the bacteria and research progress on the enantioselective biotransformation process are introduced.

Address: State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai.

DOI: 10.1007/s00253-005-0307-0

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MeSH Terms: Biotechnology, Gluconobacter oxydans, Organic Chemicals, Oxidation-Reduction