Antioxidants as novel agents for asthma.

Seoung Ju Park, Yong Chul Lee

Journal: Mini reviews in medicinal chemistry 2006;6(2):235-40

PMID: 16472191

Abstract

Oxidative stress plays an important role in the pathogenesis of asthma. Recently several investigators have studied the effects of a variety of antioxidants on asthma. Antioxidants, including L-2-oxothiazolidine-4-carboxylic acid, reduce airway inflammation and hyper-responsiveness of asthma and may be novel therapeutic agents for asthma.

Address: Department of Internal Medicine, Research Center for Allergic Immune Diseases, Chonbuk National University Medical School, Jeonju, South Korea.

DOI: 10.2174/138955706775475948

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MeSH Terms: Acetylcysteine, Anti-Asthmatic Agents, Antioxidants, Asthma, Cysteine, Glutathione, Humans, Oxidative Stress, Pyrrolidonecarboxylic Acid, Reactive Oxygen Species, Thiazoles, Thiazolidines