Diffusion-weighted imaging of the liver: technical challenges and prospects for the future.

Shinji Naganawa, Hisashi Kawai, Hiroshi Fukatsu, Yasuo Sakurai, Ikuo Aoki, Shunichi Miura, Takeo Mimura, Hitoshi Kanazawa, Takeo Ishigaki

Journal: Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine 2006;4(4):175-86

PMID: 16543702

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Abstract

Diffusion-weighted imaging (DWI) has recently been attempted in the abdominal region. We review diffusion-weighted images of the liver, especially from the technical point of view. We discuss selection of pulse sequence parameters, effects of anti-breathing motion technique, tips for measuring apparent diffusion coefficient (ADC), and utility of superparamagnetic iron oxide (SPIO), showing clinical cases, including those at 3T. Our current trial of new pulse sequencing, such as SPIO-mediated breath-holding black-blood fluid-attenuated inversion recovery (BH-BB-FLAIR), imaging is shown. Some prospects for the future in DWI of the liver are also stated.

Address: Department of Radiology, Nagoya University Graduate School of Medicine, Japan. [email protected]

DOI: 10.2463/mrms.4.175

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MeSH Terms: Adult, Aged, Contrast Media, Diffusion Magnetic Resonance Imaging, Echo-Planar Imaging, Female, Humans, Image Enhancement, Liver, Liver Diseases, Liver Neoplasms, Male, Middle Aged