Topical therapy for actinic keratoses: current and evolving therapies.

Jeffrey M Weinberg

Journal: Reviews on recent clinical trials 2008;1(1):53-60

PMID: 18393780

Abstract

Actinic keratoses (AKs) are evolving malignant cutaneous neoplasms. They are also known as solar keratosis, squamous cell carcinoma in situ-solar keratotic type, or keratinocytic intraepidermal neoplasia. Actinic keratoses can be treated by two general methods: by physical/destructive methods and with topical therapies. This article will review current and evolving topical therapeutic options for AKs. Several topical treatment options have been shown to offer some significant benefit in the alleviation of these lesions. The therapies include 5-fluorouracil, imiquimod, diclofenac, colchicine and retinoids.

Address: Department of Dermatology, St. Luke's-Roosevelt Hospital Center, New York, NY 10025, USA. [email protected]

DOI: 10.2174/157488706775246166

Link outs

Free resources

Medical:

https://medlineplus.gov/skincancer.html

Subscription / membership required

Full Text Sources:

https://www.ingentaconnect.com/openurl?genre=artic...

MeSH Terms: Administration, Cutaneous, Administration, Topical, Aminoquinolines, Antineoplastic Agents, Carcinoma in Situ, Colchicine, Diclofenac, Fluorouracil, Humans, Imiquimod, Keratosis, Neoplasms, Squamous Cell, Retinoids, Skin Neoplasms, Treatment Outcome, Ultraviolet Rays