Nutrigenomics: SNPs correlated to physical activity, response to chiropractic treatment, mood and sleep.

K Donato, G Madeo, C Micheletti, S Cristoni, M R Ceccarini, T Beccari, A Iaconelli, B Aquilanti, G Matera, K L Herbst, M Bertelli

Journal: La Clinica terapeutica 2023;174(Suppl 2(6)):183-192

PMID: 37994763

Abstract

Nutrigenomics, a rapidly evolving field that bridges genetics and nutrition, explores the intricate interactions between an individual's genetic makeup and how they respond to nutrients. At its core, this discipline focuses on investigating Single Nucleotide Polymorphisms (SNPs), the most common genetic variations, which significantly influence a person's physiological status, mood regulation, and sleep patterns, thus playing a pivotal role in a wide range of health out-comes. Through decoding their functional implications, researchers are able to uncover genetic factors that impact physical fitness, pain perception, and susceptibility to mood disorders and sleep disruptions. The integration of nutrigenomics into healthcare holds the promise of transformative interventions that cater to individual well-being. Notable studies shed light on the connection between SNPs and personalized responses to exercise, as well as vulnerability to mood disorders and sleep disturbances. Understanding the intricate interplay between genetics and nutrition informs targeted dietary approaches, molding individual health trajectories. As research advances, the convergence of genetics and nourishment is on the brink of reshaping healthcare, ushering in an era of personalized health management that enhances overall life quality. Nutrigenomics charts a path toward tailored nutritional strategies, fundamentally reshaping our approach to health preservation and preventive measures.

Address: MAGI EUREGIO, Bolzano, Italy.; MAGISNAT, Peachtree Corners (GA), USA.; MAGI'S LAB, Rovereto (TN), Italy.; ISB Ion Source & Biotechnologies srl, Italy, Bresso, Milano, Italy.; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.; UOSD Medicina Bariatrica, Fondazione Policlinico Agostino Gemelli IRCCS, Rome, Italy.; Total Lipedema Care, Beverly Hills, California, and Tucson, Arizona, USA.; MAGI EUREGIO, Bolzano, Italy.; MAGISNAT, Peachtree Corners (GA), USA.; MAGI'S LAB, Rovereto (TN), Italy.
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