Hyponatremia in patients with heart failure.

Mihai Gheorghiade, Cesare Orlandi, Francesco Fedele, Liviu Klein, James E Udelson, Gennaro Sardella, Leonardo De Luca

Journal: The American journal of cardiology 2006;96(12A):19L-23L

PMID: 16399089

Full Text on Elsevier Science View on PubMed

Abstract

Mild hyponatremia is encountered frequently in patients hospitalized for worsening heart failure. Admission plasma sodium concentration appears to be an independent predictor of increased mortality after discharge and rehospitalization. Recent studies have suggested that correction of hyponatremia may be associated with improved survival. This hypothesis is currently being studied in large prospective randomized clinical trials.

Address: Department of Cardiovascular and Respiratory Sciences, La Sapienza University, Rome, Italy.

DOI: 10.1016/j.amjcard.2005.09.066