Schizophrenia: an update and review.

Jehannine Austin

Journal: Journal of genetic counseling 2006;14(5):329-40

PMID: 16195940

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Abstract

Schizophrenia is a common complex disorder characterized by psychosis, cognitive dysfunction and negative symptoms, whose etiology involves interactions between both genetic and environmental vulnerability factors. Recently, ongoing research attempting to elucidate the nature of these vulnerability factors has been generating exciting findings. The advances in understanding of environmental risk factors for mental illnesses and in genetic research into mental illnesses will be reviewed. Limitations of the findings and implications of these advances for genetic counseling practice will also be discussed.

Address: Department of Psychiatry, University of British Columbia, Vancouver, B.C., Canada. [email protected]

DOI: 10.1007/s10897-005-1622-4

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MeSH Terms: Birth Rate, Carrier Proteins, Catechol O-Methyltransferase, Cognition Disorders, D-Amino-Acid Oxidase, Diagnostic and Statistical Manual of Mental Disorders, Dysbindin, Dystrophin-Associated Proteins, Genetic Predisposition to Disease, Humans, Nerve Tissue Proteins, Neuregulin-1, Psychotic Disorders, RGS Proteins, Receptors, Dopamine D3, Risk Factors, Schizophrenia, Seasons, Stress, Psychological