Effect of Lumenato a Tomato derived oral supplement on improving skin barrier strength.

Elizabeth Tarshish, Karin Hermoni, Neelam Muizzuddin

Journal: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2023;29(11):e13504

PMID: 38009018

Abstract

INTRODUCTION

Improvement of skin barrier strength could lead to healthy and youthful appearance. "Beauty inside-out" approach using nutraceuticals such as tomato derived carotenoids to support skin barrier strength could be of benefit to the ageing population.

METHOD

A panel of 60 female subjects were provided with the Lumenato capsules (containing carotenoids) or placebo capsules as nutritional supplements for 3 months. Skin health and barrier function were observed using evaporimeter which measures trans epidermal water loss (TEWL). Barrier strength was determined by study of the number of strippings required to disrupt skin barrier and barrier repair was observed in terms of TEWL a few hours after barrier disruption. Cutometer was used to observe skin firmness and elasticity. Measurements were obtained before treatment and after 4 and 12 weeks of use.

RESULTS

Results indicated a statistically significant improvement (p < 0.05) in skin barrier strength; a higher number of strippings were required to disrupt skin barrier after 12 weeks of supplement use. There was also a significant improvement in skin firmness and elasticity as observed with a cutometer.

CONCLUSION

Based on the confines and conditions of this study, oral supplementation with Lumenato resulted in significant improvement in skin barrier as well as skin firmness and elasticity.

© 2023 Lycored. Skin Research and Technology published by John Wiley & Sons Ltd.

Address: Lycored Ltd, Beer Sheva, Israel.; Lycored CORP, Secaucus, New Jersey, USA.; Skin Clinical Research Consultants LLC, Bethpage, New York, USA.
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