Subanesthetic ketamine: how it alters physiology and behavior in humans.

Laura M Rowland

Journal: Aviation, space, and environmental medicine 2005;76(7 Suppl):C52-8

PMID: 16018330

Abstract

Ketamine is a drug that is commonly used for anesthesia and analgesia worldwide. Although it has an excellent safety profile, cognitive and psychotomimetic adverse effects are commonly associated with its administration. This review describes the clinical applications, potential adverse events, neurobiological, and behavioral effects of ketamine used at subanesthetic doses in humans.

Address: Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA. [email protected]

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MeSH Terms: Behavior, Brain, Cognition, Excitatory Amino Acid Antagonists, Humans, Ketamine, Learning, Memory