Role of parenteral nutrition in cancer patients undergoing high-dose chemotherapy followed by autologous peripheral blood progenitor cell transplantation.

Alfredo Tartarone, Jenna Wunder, Gianpiero Romano, Raffaele Ardito, Giovanni Iodice, Silvia Mazzuoli, Marialucia Barone, Rosella Matera, Nicola Di Renzo

Journal: Tumori 2005;91(3):237-40

PMID: 16206647

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Abstract

High-dose chemotherapy followed by autologous bone marrow or peripheral blood progenitor cell transplantation represents a recognized option in the treatment of solid tumors and hematologic diseases. Patients receiving high-dose chemotherapy are traditionally supported with parenteral nutrition with the aim to prevent malnutrition secondary to gastrointestinal toxicity and metabolic alterations induced by the conditioning regimens. Nevertheless, well-defined guidelines for its use in this clinical setting are lacking and there are several areas of controversy.

Address: Division of Medical Oncology and Hematology,Centro di Riferimento Oncologico della Basilicata (CROB), Rionero in Vulture (PZ), Italy. [email protected]

DOI: 10.1177/030089160509100305

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MeSH Terms: Antineoplastic Combined Chemotherapy Protocols, Humans, Neoplasms, Nutrition Disorders, Parenteral Nutrition, Peripheral Blood Stem Cell Transplantation, Practice Guidelines as Topic, Risk Factors, Transplantation, Autologous