Kate Morgan, Sarah E Flanagan, Clare Gilbert, Niamh Gilligan, Caroline Hall, Jayne Houghton, Ritika Kapoor, Helen McDevitt, Zainab Mohamed, Karen Erlandson-Parry, Jacqueline Nicholson, Ana Nikiforovski, Elaine O'Shea, Pratik Shah, Kirsty Wilson, Chris Worth, Sarah Worthington, Indraneel Banerjee, Neelam Awan, Angela K Lucas-Herald, Antonia Dastamani, Maria Salomon Estebanez, Senthil Senniappan, Noina Abid, Sumera Ahmad, Sophie Alexander, Bindu Avatapalle, M Guftar Shaikh, Hester Blair, Roisin Boyle, Alexander Chesover, Barbara Cochrane, Ross Craigie, Annaruby Cunjamalay, Sarah Dearman, Paolo De Coppi
Journal: Frontiers in endocrinology 2023;14():1231043
PMID: 38027197
Congenital hyperinsulinism (CHI) is a condition characterised by severe and recurrent hypoglycaemia in infants and young children caused by inappropriate insulin over-secretion. CHI is of heterogeneous aetiology with a significant genetic component and is often unresponsive to standard medical therapy options. The treatment of CHI can be multifaceted and complex, requiring multidisciplinary input. It is important to manage hypoglycaemia in CHI promptly as the risk of long-term neurodisability arising from neuroglycopaenia is high. The UK CHI consensus on the practice and management of CHI was developed to optimise and harmonise clinical management of patients in centres specialising in CHI as well as in non-specialist centres engaged in collaborative, networked models of care. Using current best practice and a consensus approach, it provides guidance and practical advice in the domains of diagnosis, clinical assessment and treatment to mitigate hypoglycaemia risk and improve long term outcomes for health and well-being.
Copyright © 2023 Shaikh, Lucas-Herald, Dastamani, Salomon Estebanez, Senniappan, Abid, Ahmad, Alexander, Avatapalle, Awan, Blair, Boyle, Chesover, Cochrane, Craigie, Cunjamalay, Dearman, De Coppi, Erlandson-Parry, Flanagan, Gilbert, Gilligan, Hall, Houghton, Kapoor, McDevitt, Mohamed, Morgan, Nicholson, Nikiforovski, O'Shea, Shah, Wilson, Worth, Worthington and Banerjee.
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