Sodium transport in airway epithelium correlates with lung compliance in healthy newborn infants.

Otto Helve, Olli Pitkänen, Turkka Kirjavainen, Sture Andersson

Journal: The Journal of pediatrics 2005;146(2):273-6

PMID: 15689923

Full Text on Elsevier Science View on PubMed

Abstract

To study the relation between sodium transport in airway epithelium and postnatal pulmonary adaptation, we measured nasal potential difference at 1 to 4 hours and lung compliance at 21 to 48 hours after birth in 20 healthy infants. Sodium transport correlated with lung compliance ( r 2 = 0.40, P < .003). Airway sodium transport plays a role in postnatal pulmonary adaptation.

Address: Department of Neonatology, Hospital for Children and Adolescents, Helsinki University Central Hospital, 00029-HUS, Helsinki, Finland.

DOI: 10.1016/j.jpeds.2004.09.024

Link outs

Subscription / membership required

Full Text Sources:

MeSH Terms: Epithelial Cells, Female, Humans, Infant, Newborn, Ion Transport, Lung Compliance, Male, Respiratory Mucosa, Sodium