Utilizing proteomics to identify and optimize microalgae strains for high-quality dietary protein: a review.

Sara Hamzelou, Damien Belobrajdic, James A Broadbent, Angéla Juhász, Kim Lee Chang, Ian Jameson, Peter Ralph, Michelle L Colgrave

Journal: Critical reviews in biotechnology 2024;44(7):1280-1295

PMID: 38035669

Abstract

Algae-derived protein has immense potential to provide high-quality protein foods for the expanding human population. To meet its potential, a broad range of scientific tools are required to identify optimal algal strains from the hundreds of thousands available and identify ideal growing conditions for strains that produce high-quality protein with functional benefits. A research pipeline that includes proteomics can provide a deeper interpretation of microalgal composition and biochemistry in the pursuit of these goals. To date, proteomic investigations have largely focused on pathways that involve lipid production in selected microalgae species. Herein, we report the current state of microalgal proteome measurement and discuss promising approaches for the development of protein-containing food products derived from algae.

Address: CSIRO Health & Biosecurity, Adelaide, Australia.; CSIRO Agriculture and Food, St Lucia, Australia.; School of Science, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Edith Cowan University, Joondalup, Australia.; CSIRO Ocean and Atmosphere, Hobart, Australia.; Climate Change Cluster, University of Technology Sydney, Ultimo, Australia.
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