Role of [18F]-dopa-PET imaging in assessing movement disorders.

Alan J Fischman

Journal: Radiologic clinics of North America 2005;43(1):93-106

PMID: 15693650

Full Text on Elsevier Science View on PubMed

Abstract

FD-PET has proved to be an extremely useful technique for the noninvasive evaluation of nigrostriatal pathophysiology in patients with PD and other movement disorders. The development of ratio methods for image analysis has greatly reduced the complexity of these PET studies and has facilitated data analysis. With the recent advances in cyclotron targetry and automated synthesis modules FD-PET will soon become an important component of the clinical armamentarium.

Address: Division of Nuclear Medicine, Department of Radiology, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA. [email protected]

DOI: 10.1016/j.rcl.2004.08.002

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MeSH Terms: Dihydroxyphenylalanine, Dopamine Agonists, Fluorine Radioisotopes, Humans, Parkinson Disease, Positron-Emission Tomography