Making sense of nonsense: the evolution of selenocysteine usage in proteins.

Paul R Copeland

Journal: Genome biology 2006;6(6):221

PMID: 15960811

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Abstract

A recent analysis of sequences derived from organisms in the Sargasso Sea has revealed a surprisingly different set of selenium-containing proteins than that previously found in sequenced genomes and suggests that selenocysteine utilization has been lost by many groups of organisms during evolution.

Address: Department of Molecular Genetics, Microbiology and Immunology, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA. [email protected]

DOI: 10.1186/gb-2005-6-6-221

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https://genomebiology.biomedcentral.com/articles/1...
https://pmc.ncbi.nlm.nih.gov/articles/pmid/1596081...
https://europepmc.org/abstract/MED/15960811

MeSH Terms: Bacterial Proteins, Databases, Protein, Evolution, Molecular, Genes, Bacterial, Selenocysteine