Recent progress in polysaccharide and polypeptide based modern moisture-retentive wound dressings.

N P Swetha Menon, M Kamaraj, M Anish Sharmila, M Govarthanan

Journal: International journal of biological macromolecules 2024;256(Pt 2):128499

PMID: 38048932

Abstract

Wounds were considered as defects in the tissues of the human skin and wound healing is said to be a tedious process as there are possibilities of infection or inflammation due to microorganisms. Modern moisture-retentive wound dressing (MMRWD) is opening a new window toward wound therapy. It comprises different types of wound dressing that has classified based on their functionality. Selective polysaccharide-polypeptide fiber composite materials such as hydrogels, hydrocolloids, hydro fibers, transparent-film dressing, and alginate dressing are discussed in this review as a type of MMRWD. The highlight of this polysaccharide and polypeptide based MMRWD is that it supports and enhances the healing of different types of wounds by moisture absorption thus preventing infection. This study has given enlightenment on the application of selected polysaccharide and polypeptide based MMRWD that enhances wound healing actions still it has been observed that the composite wound healing dressing is more effective than the single one. The nano-sized materials (synthetic nano drugs and phyto drugs) were found to increase the efficiency of healing action while coated in the wound dressing material. Future research is required to find out more possibilities of the different composite types of wound dressing in the healing action.

Copyright © 2023 Elsevier B.V. All rights reserved.

Address: Department of Fashion Designing, Faculty of Science and Humanities, SRM Institute of Science and Technology -Ramapuram, Chennai 600089, Tamil Nadu, India; Department of Fashion Design and Arts, Hindustan Institute of Technology and Science, Deemed to be University, Chennai 603103, Tamil Nadu, India.; Department of Biotechnology, Faculty of Science and Humanities, SRM Institute of Science and Technology -Ramapuram, Chennai 600089, Tamil Nadu, India; Life Science Division, Faculty of Health and Life Sciences, INTI International University, Nilai 71800, Malaysia. Electronic address: [email protected].; Department of Fashion Design and Arts, Hindustan Institute of Technology and Science, Deemed to be University, Chennai 603103, Tamil Nadu, India. Electronic address: [email protected].; Department of Environmental Engineering, Kyungpook National University, Daegu 41566, Republic of Korea; Department of Biomaterials, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 600 077, India.

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