The clinical application of metabolic therapy for cardiovascular disease.

Salvatore Pepe, Franklin Rosenfeldt, Anthony Hadj

Journal: Heart, lung & circulation 2008;16 Suppl 3():S56-64

PMID: 17618830

Full Text on Elsevier Science View on PubMed

Abstract

Metabolic therapy involves the administration of a substance normally found in the body to enhance a metabolic reaction within the cell. This may be achieved in two ways. Firstly, for some systems a substance can be given to achieve greater than normal levels in the body so as to drive an enzymic reaction in a preferred direction. Secondly, metabolic therapy may be used to correct an absolute or relative deficiency of a cellular component. Thus, metabolic therapy differs greatly from most standard cardiovascular pharmacologic therapies such as the use of ACE Inhibitors, beta-blockers, statins and calcium channel antagonists that are given to block rather than enhance cellular processes.

Address: Cardiac Surgical Research Unit, Department of Cardiothoracic Surgery, Alfred Hospital and Baker Heart Research Institute, Victoria, Australia.

DOI: 10.1016/j.hlc.2007.04.001

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MeSH Terms: Adaptation, Physiological, Cardiovascular Diseases, Coenzymes, Exercise, Glucose, Heart Failure, Humans, Hypertension, Insulin, Meditation, Orotic Acid, Physical Therapy Modalities, Potassium, Thioctic Acid, Ubiquinone