Application of microarrays in high-throughput enzymatic profiling.

Mahesh Uttamchandani, Xuan Huang, Grace Y J Chen, Lay-Pheng Tan, Shao Q Yao

Journal: Molecular biotechnology 2005;28(3):227-39

PMID: 15542923

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Abstract

This review focuses on recent developments in microarray-based technologies for high-throughput screenings of enzymes. Novel methods of protein immobilization, detection of enzymatic activities, and inhibitions were highlighted.

Address: Department of Biological Sciences, National University of Singapore, 3 Science Drive, Singapore 117543, Republic of Singapore.

DOI: 10.1385/MB:28:3:227

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MeSH Terms: Amino Acid Sequence, Enzymes, Oligonucleotide Array Sequence Analysis