Telithromycin-induced acute interstitial nephritis: a first case report.

Michel Tintillier, Lotti Kirch, Carole Almpanis, Jean-Pierre Cosyns, Jean-Michel Pochet, Charles Cuvelier

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 2005;44(2):e25-27

PMID: 15264209

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Abstract

Telithromycin, a ketolide antibiotic used for the treatment of community-acquired respiratory infections, is widely prescribed in primary care practice. Treatment-related adverse events are mainly of gastrointestinal origin and generally mild in intensity. The authors report the first case of telithromycin-induced severe acute interstitial nephritis. Practitioners should be aware of the possibility that telithromycin therapy could result in this form of drug-induced acute renal failure.

Address: Department of Nephrology, Clinique et Maternité Sainte Elisabeth, Namur, Belgium. [email protected]

DOI: 10.1053/j.ajkd.2004.04.045

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MeSH Terms: Acute Disease, Adolescent, Humans, Ketolides, Kidney, Male, Methylprednisolone, Nephritis, Interstitial, Respiratory Tract Infections