Three-week clinical trial of a 14% hydrogen-peroxide, strip-based bleaching system.

Edward J Swift, Patricia A Miguez, Matthew L Barker, Robert W Gerlach

Journal: Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 2005;25(8 Suppl 2):27-32

PMID: 15645892

Abstract

This clinical trial tested the efficacy and safety of a professional strip-based whitening system (Crest Whitestrips Supreme) using the manufacturer's recommended 3-week treatment regimen. These strips have a higher concentration, but a similar amount of hydrogen peroxide relative to Crest Professional Whitestrips, because the thickness of the gel on strips is reduced. Tooth whitening was measured using the value-oriented VITA Classic Shade Guide before and after treatment. Twenty-nine subjects were treated with either Crest Whitestrips Supreme or placebo strips that did not contain hydrogen peroxide. Participants in the experimental group achieved a mean lightening of nearly eight VITA shades relative to placebo, with minimal side effects.

Address: Department of Operative Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA.

MeSH Terms: Adult, Aged, Double-Blind Method, Drug Delivery Systems, Female, Follow-Up Studies, Gels, Gingiva, Humans, Hydrogen Peroxide, Male, Maxilla, Middle Aged, Oxidants, Tooth Bleaching, Tooth Discoloration, Toothache, Treatment Outcome