Harnessing the power of nutritional antioxidants against adrenal hormone imbalance-associated oxidative stress.

Anil Patani, Deepak Balram, Virendra Kumar Yadav, Kuang-Yow Lian, Ashish Patel, Dipak Kumar Sahoo

Journal: Frontiers in endocrinology 2023;14():1271521

PMID: 38098868

Abstract

Oxidative stress, resulting from dysregulation in the secretion of adrenal hormones, represents a major concern in human health. The present review comprehensively examines various categories of endocrine dysregulation within the adrenal glands, encompassing glucocorticoids, mineralocorticoids, and androgens. Additionally, a comprehensive account of adrenal hormone disorders, including adrenal insufficiency, Cushing's syndrome, and adrenal tumors, is presented, with particular emphasis on their intricate association with oxidative stress. The review also delves into an examination of various nutritional antioxidants, namely vitamin C, vitamin E, carotenoids, selenium, zinc, polyphenols, coenzyme Q10, and probiotics, and elucidates their role in mitigating the adverse effects of oxidative stress arising from imbalances in adrenal hormone levels. In conclusion, harnessing the power of nutritional antioxidants has the potential to help with oxidative stress caused by an imbalance in adrenal hormones. This could lead to new research and therapeutic interventions.

Copyright © 2023 Patani, Balram, Yadav, Lian, Patel and Sahoo.

Address: Department of Biotechnology, Smt. S.S. Patel Nootan Science and Commerce College, Sankalchand Patel University, Visnagar, Gujarat, India.; Department of Electrical Engineering, National Taipei University of Technology, Taipei, Taiwan.; Department of Life Sciences, Hemchandracharya North Gujarat University, Gujarat, India.; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.
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