Teleworking as the main risk factor for sedentary behavior: the COVISTRESS international study.

Hijrah Nasir, Martine Duclos, Bruno Pereira, David Thivel, Jiao Jiao, Binh Quach, Reza Bagheri, Marek Zak, Ukadike Chris Ugbolue, Julien S Baker, Alistair Cole, Martial Mermillod, Morteza Charkhabi, Maëlys Clinchamps, Frederic Dutheil

Journal: PloS one 2026;21(9):e0356764

PMID: 42721213

Abstract

BACKGROUND

If teleworking is already associated with prolonged sedentary behavior, the literature lacks an integrating model with all putative influencing variables, as well as a sufficient number of participants to explore extreme sitting behavior. Therefore, we aimed to investigate the influence of teleworking on sitting time, considering main sociodemographic, occupational and lifestyle factors.

METHODS

The COVISTRESS study is an international observational study, using self-reported questionnaires (REDCap® software). We used linear and logistic multivariate model to assess the impact of telework on sitting time concomitantly with other sociodemographic, occupational, and lifestyle variables.

RESULTS

6,653 respondents were included. The mean sitting time was 5.6 ± 3.4h/day, with 15.2% of respondents sitting for >8-14h/day and 1.6% sitting >14 hours/day. Workers who teleworked 0%, 1-25%, 26-50%, 51-75%, 76-99%, and 100% respectively sat on average 4.9 ± 3.2h/day, 5.8 ± 3.2h/day, 6.4 ± 3.1h/day, 6.5 ± 3.8h/day, 7.6 ± 3.5h/day, and 9.1 ± 4.3h/day, and the prevalence of workers sitting >14h/day increased from 1.5%, 1.9%, 0.4%, 3.2%, 5.4% to 10.7%. Compared with workers who did not telework, the risk of sitting 8-14 h/day was multiplied by 1.9 (1.2 to 3.0) for people working 1-25% in telework, by 4.7 (2.2 to 9.7) for people working 26-50% in telework, by 4.3 (1.5 to 12.2) for people working 51-75% in telework, and by 9.2 (1.6 to 51.5) for people working >75% in telework; the risk of sitting ≥ 14h/day was multiplied by 5.8 (1.07 to 31.5) for people working 51-75% in telework and dramatically increased by 34.3 (3.71 to 317) for people working >75% in telework in multivariate model.

CONCLUSION

Teleworking is the strongest risk factor for high sitting time, with a marked dose-response relation. While several other sociodemographic, occupational, and lifestyle factors showed association with sitting time in univariate model, many of these relationships weakened or disappeared in the multivariate models, except telework that remained the most consistent determinants of sedentary behavior when concomitantly put together with all other variables.

TRIAL REGISTRATION

ClinicalTrials.gov NCT04538586.

Copyright: © 2026 Nasir et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Address: Université Clermont Auvergne, Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), CNRS LaPSCo, CHU Clermont-Ferrand, Clermont-Ferrand, France.; Université Clermont Auvergne, INRAE, UNH, CHU Clermont-Ferrand, Sport Medicine and Functional Exploration, Clermont-Ferrand, France.; CHU Clermont-Ferrand, Biostatistics, Clinical Research Direction, Clermont-Ferrand, France.; Université Clermont Auvergne, Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), Clermont-Ferrand, France.; Hong Kong Baptist University, Sport and Physical Education, Hong KongChina.; University of Isfahan, Exercise Physiology, Isfahan, Iran.; The Jan Kochanowski University, Faculty of Medicine and Health Sciences, Institute of Physiotherapy, Kielce, Poland.; University of the West of Scotland, School of Health and Life Sciences, Institute for Clinical Exercise & Health Science, South Lanarkshire, Glasgow, United Kingdom.; Hong Kong Baptist University, Centre for Health and Exercise Science Research, Hong Kong, China.; Université Lumière - Lyon 2, SciencePo Lyon, Lyon, France.; Université Grenoble Alpes, Université Savoie Mont Blanc, CNRS, LPNC, 38000 Grenoble, France.; HSE University, Moscow, Russia.; Université Clermont Auvergne, CNRS, LaPSCo, Physiological and Psychosocial Stress, CHU Clermont-Ferrand, Occupational and Environmental Medicine, Clermont-Ferrand, France.
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