Complications of Transcatheter Aortic Valve Replacement: Contemporary Prevention, Recognition, and Management.

Sant Kumar, Arturo Giacaman, Pedro A Villablanca

Journal: Interventional cardiology clinics 2026;15(4):647-656

PMID: 42648866

Abstract

This review summarizes contemporary prevention, recognition, and management of major complications after transcatheter aortic valve replacement. The article emphasizes anatomy-specific planning with multidetector computated tomography (CT) to assess annular and left ventricular outflow tract (LVOT) calcium, coronary obstruction risk, aortic root dimensions, access quality, and factors affecting valve selection and deployment. It reviews key complications including annular and aortic root injury, coronary obstruction, valve malposition or embolization, paravalvular regurgitation, ventricular perforation and tamponade, dynamic LVOT obstruction, mitral injury, and iatrogenic septal defects. The review also highlights the importance of postevent surveillance for delayed complications after apparent procedural stabilization.

Address: Creighton University School of Medicine, Phoenix, AZ, USA. Electronic address: [email protected].; Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA; Michigan State University, College of Human Medicine.; Division of Cardiovascular Medicine, Henry Ford Hospital, Henry Ford Health System, Detroit, MI, USA; College of Human Medicine, Michigan State University, East Lansing, MI, USA.

DOI: 10.1016/j.iccl.2026.06.005

Link outs

Free resources

Medical:

https://medlineplus.gov/aftersurgery.html

MeSH Terms: Humans, Transcatheter Aortic Valve Replacement, Postoperative Complications, Aortic Valve Stenosis, Aortic Valve, Heart Valve Prosthesis