Evaluating the efficacy of I-fiber pearl on reducing body fat accumulation in obese females: A randomized, double-blind, and placebo-controlled trial.

Hung-Hsuan Kuo, Chia-Chun Chen, Ching-Chang Cho, Chun-Tse Tsai, Shiuan-Chih Chen, Chin-Lin Hsu

Journal: Journal of food and drug analysis 2026;34(2):159-171

PMID: 42485520

Abstract

Obesity is a growing public health challenge worldwide, strongly linked to metabolic syndrome, type 2 diabetes, and cardiovascular disease. Inulin, a soluble, fermentable fiber derived mainly from Jerusalem artichoke and chicory, has been reported to improve weight management and metabolic health. This randomized, double-blind, placebo-controlled trial evaluated the effects of inulin-enriched tapioca pearls (I-fiber pearl) on body composition and lipid parameters in obese women. Methods: Fifty women (BMI ≥27 or waist >80 cm; age 20-50 years) were randomized to receive either I-fiber pearl or placebo (2 packs/day, 100 g/pack) for 12 weeks. Anthropometric indices, body composition, and blood biochemistry were assessed pre- and post-intervention. Results: After 12 weeks, the I-fiber group showed significant reductions in body weight, BMI, body fat mass, visceral fat, total cholesterol, and LDL cholesterol. I-fiber pearl improved body composition and lipid profiles, suggesting potential benefits as a functional supplement for obesity management.

Address: Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan.; Itsway Biotech Inc., Taipei, Taiwan.; Institute of Medicine and School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Family and Community Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan.; Department of Nutrition, Chung Shan Medical University Hospital, Taichung, Taiwan.
Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.