Hypothetical hypercholesterolaemia and atherosclerosis.

W E Stehbens

Journal: Medical hypotheses 2004;62(1):72-8

PMID: 14729007

Full Text on Elsevier Science View on PubMed

Abstract

Recent pathological advances in experimental and iatrogenic atherosclerosis and critical review of the epidemiology of coronary heart disease revealed fallacious data and methodological errors underlying the hypercholesterolaemia/lipid hypothesis. Misuse of risk factors, inappropriate use of surrogates and misinterpretation of data pertaining to cholesterol's role in atherogenesis necessitate greater precision in word usage and terminology, reinstitution of the statistical reference range for cholesterol and closer scientific surveillance of aetiological endeavours in medicine.

Address: Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, PO Box 7343, Wellington South, Wellington, New Zealand. [email protected]

DOI: 10.1016/s0306-9877(03)00267-6

Link outs

Free resources

Medical:

https://medlineplus.gov/cholesterol.html

Subscription / membership required

Full Text Sources:

https://linkinghub.elsevier.com/retrieve/pii/S0306...

MeSH Terms: Arteriosclerosis, Causality, Cholesterol, Comorbidity, Coronary Artery Disease, Epidemiologic Research Design, Evidence-Based Medicine, Humans, Hypercholesterolemia, Risk Assessment, Risk Factors