Nutritional management in functional dyspepsia and gastroparesis.

Stine Störsrud, Joost P Algera, Hans Törnblom

Journal: Best practice & research. Clinical gastroenterology 2025;79():102079

PMID: 41423314

Abstract

Functional dyspepsia (FD) and gastroparesis (GP) are chronic upper gastrointestinal disorders in which symptoms are closely linked to food intake. However, dietary interventions remain insufficiently studied, and the clinical overlap between the two conditions poses challenges for study design and interpretation. This review summarizes current evidence on the impact of eating behaviors, specific diets and food items, and macronutrient composition on symptom generation in FD and GP, and considers how these findings may inform nutritional management strategies. While emerging data suggest potential dietary approaches, evidence-based recommendations remain limited. Well-designed randomized controlled trials with standardized diagnostic criteria, validated outcome measures, and integration of physiological biomarkers are urgently needed to establish effective, individualized dietary interventions for these disorders.

Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.

Address: Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Department of Medicine, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Department of Medicine, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden. Electronic address: [email protected].

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