Innovative Biomechanical Design and Performance of Carbon Fiber-Thermoplastic Implants via Additive Manufacturing.

Vacharat Thongsumrit, Phorntep Chaitaweepakorn, Pajjittar Kolimart, Khomkrit Pingkarawat, Wares Chancharoen, Sontipee Aimmanee

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 2025;113(11):e35682

PMID: 41185401

Abstract

This study explores the potential of 3D-printed carbon fiber-reinforced thermoplastic composites, specifically Nylon and PEEK, as advanced materials for medical implants. Fabricated using fused filament fabrication (FFF), these implants were evaluated against conventional Ti-6AL-4V titanium alloy counterparts through a combination of experimental analysis and finite element method (FEM) simulations. The novel designs of discontinuous carbon fiber-PEEK and continuous carbon fiber-Nylon composites exhibited enhanced performance, reducing screw pull-out force by nearly 50% relative to Ti-6AL-4V. Furthermore, the thermoplastic composites demonstrated significantly higher bio-elastic coupling strain energy density (SED), indicating superior capacity to promote bone healing and callus formation. A comprehensive multi-criteria evaluation-including metrics on screw loosening, bone remodeling, and resorption-revealed that the 3D-printed composites outperformed titanium by 33%-65%. These results provide design guidelines for FFF 3D-printed composite implants, offering considerable promise as customizable and effective alternatives to conventional metal implants.

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Address: Advanced Materials and Structures Laboratory (AMASS) and Center for Lightweight Materials Design and Manufacturing, Department of Mechanical Engineering, Faculty of Engineering, King Mongkut's University of Technology Thonburi, Thung Khru, Bangkok, Thailand.; PTT Global Chemical Public Company Limited, Bangkok, Thailand.; Laboratory of Artificial Intelligence and Innovation in Medicine (AIIM), Princess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.
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